Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice

Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice

Introduction: T helper 17 (Th17) has been implicated in a variety of inflammatory lung and immune system diseases. However, little is known about the expression and biological role of IL-17 in acute lung injury (ALI). We investigated the mechanisms involved in the effect of anti-IL17 in a model of l...

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Main Authors: Renato Fraga Righetti, Tabata Maruyama dos Santos, Leandro do Nascimento Camargo, Luciana Ritha Cássia Rolim Barbosa Aristóteles, Silvia Fukuzaki, Flávia Castro Ribas de Souza, Fernanda Paula Roncon Santana, Marcus Vinicius Rodrigues de Agrela, Maysa Mariana Cruz, Maria Isabel Cardoso Alonso-Vale, Isabella Santos Genaro, Beatriz Mangueira Saraiva-Romanholo, Edna Aparecida Leick, Milton de Arruda Martins, Carla Máximo Prado, Iolanda de Fátima Lopes Calvo Tibério
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
acute lung injury
inflammation mediators
interleukin 17
remodeling
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01021/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01021/full

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