qtQDA: quantile transformed quadratic discriminant analysis for high-dimensional RNA-seq data
Classification on the basis of gene expression data derived from RNA-seq promises to become an important part of modern medicine. We propose a new classification method based on a model where the data is marginally negative binomial but dependent, thereby incorporating the dependence known to be pre...
Main Authors: | Necla Koçhan, G. Yazgi Tutuncu, Gordon K. Smyth, Luke C. Gandolfo, Göknur Giner |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2019-12-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/8260.pdf |
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