Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disea...
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Mashhad University of Medical Sciences
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doaj-391faabc1ee44221923e3e01e67081f62020-11-24T22:46:48ZengMashhad University of Medical SciencesIranian Journal of Otorhinolaryngology2251-72512251-726X2016-03-0128213513910.22038/ijorl.2016.65446544Prevalence of Associated Anomalies in Cleft Lip and/or Palate PatientsShahin Abdollahi Fakhim0Nikzad Shahidi1Alireza Lotfi2Department of Otorhinolaryngology Head and Neck Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Otorhinolaryngology Head and Neck Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Otorhinolaryngology Head and Neck Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnostic procedure used. In this study we determined the prevalence of associated anomalies in patients with a cleft lip and/or palate, with a specific focus on cardiac anomalies. Materials and Methods: In this cross-sectional study, 526 patients with a cleft lip and /or palate admitted to the children’s referral hospital between 2006 and 2011 were evaluated. All associated anomalies were detected and recorded. Patient information collected included age, gender, type and side of cleft, craniofacial anomalies and presence of other anomalies, including cardiac anomalies. Data were analyzed using SPSS version 16. Results: Of the 526 patients enrolled in the study, 58% (305) were male and 42% (221) were female. In total, 75% of patients (396) were aged between 4 and 8 years and 25% (130) were aged less than 4 years. The most common cleft type in our study was bilateral cleft palate. The most commonly associated anomaly among cleft patients, in 12% of cleft patients, was a cardiac anomaly. The most common cardiac anomaly was atrial septal defect (ASD). Conclusion: The prevalence of associated anomalies among orofacial cleft patients is high. The most common associated anomaly is cardiac anomaly, with ASD being the most common cardiac anomaly. There are no significant relationships between type of cleft and associated cardiac anomalies.http://ijorl.mums.ac.ir/article_6544_3cbb4f7d2774af11e047afb916a7b36c.pdfAnomalyCardiacCleftOro-facial |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shahin Abdollahi Fakhim Nikzad Shahidi Alireza Lotfi |
spellingShingle |
Shahin Abdollahi Fakhim Nikzad Shahidi Alireza Lotfi Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients Iranian Journal of Otorhinolaryngology Anomaly Cardiac Cleft Oro-facial |
author_facet |
Shahin Abdollahi Fakhim Nikzad Shahidi Alireza Lotfi |
author_sort |
Shahin Abdollahi Fakhim |
title |
Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients |
title_short |
Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients |
title_full |
Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients |
title_fullStr |
Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients |
title_full_unstemmed |
Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients |
title_sort |
prevalence of associated anomalies in cleft lip and/or palate patients |
publisher |
Mashhad University of Medical Sciences |
series |
Iranian Journal of Otorhinolaryngology |
issn |
2251-7251 2251-726X |
publishDate |
2016-03-01 |
description |
Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnostic procedure used. In this study we determined the prevalence of associated anomalies in patients with a cleft lip and/or palate, with a specific focus on cardiac anomalies. Materials and Methods: In this cross-sectional study, 526 patients with a cleft lip and /or palate admitted to the children’s referral hospital between 2006 and 2011 were evaluated. All associated anomalies were detected and recorded. Patient information collected included age, gender, type and side of cleft, craniofacial anomalies and presence of other anomalies, including cardiac anomalies. Data were analyzed using SPSS version 16. Results: Of the 526 patients enrolled in the study, 58% (305) were male and 42% (221) were female. In total, 75% of patients (396) were aged between 4 and 8 years and 25% (130) were aged less than 4 years. The most common cleft type in our study was bilateral cleft palate. The most commonly associated anomaly among cleft patients, in 12% of cleft patients, was a cardiac anomaly. The most common cardiac anomaly was atrial septal defect (ASD). Conclusion: The prevalence of associated anomalies among orofacial cleft patients is high. The most common associated anomaly is cardiac anomaly, with ASD being the most common cardiac anomaly. There are no significant relationships between type of cleft and associated cardiac anomalies. |
topic |
Anomaly Cardiac Cleft Oro-facial |
url |
http://ijorl.mums.ac.ir/article_6544_3cbb4f7d2774af11e047afb916a7b36c.pdf |
work_keys_str_mv |
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