Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients

Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disea...

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Main Authors: Shahin Abdollahi Fakhim, Nikzad Shahidi, Alireza Lotfi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-03-01
Series:Iranian Journal of Otorhinolaryngology
Subjects:
Online Access:http://ijorl.mums.ac.ir/article_6544_3cbb4f7d2774af11e047afb916a7b36c.pdf
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spelling doaj-391faabc1ee44221923e3e01e67081f62020-11-24T22:46:48ZengMashhad University of Medical SciencesIranian Journal of Otorhinolaryngology2251-72512251-726X2016-03-0128213513910.22038/ijorl.2016.65446544Prevalence of Associated Anomalies in Cleft Lip and/or Palate PatientsShahin Abdollahi Fakhim0Nikzad Shahidi1Alireza Lotfi2Department of Otorhinolaryngology Head and Neck Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Otorhinolaryngology Head and Neck Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Otorhinolaryngology Head and Neck Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnostic procedure used. In this study we determined the prevalence of associated anomalies in patients with a cleft lip and/or palate, with a specific focus on cardiac anomalies. Materials and Methods: In this cross-sectional study, 526 patients with a cleft lip and /or palate admitted to the children’s referral hospital between 2006 and 2011 were evaluated. All associated anomalies were detected and recorded. Patient information collected included age, gender, type and side of cleft, craniofacial anomalies and presence of other anomalies, including cardiac anomalies. Data were analyzed using SPSS version 16.   Results: Of the 526 patients enrolled in the study, 58% (305) were male and 42% (221) were female. In total, 75% of patients (396) were aged between 4 and 8 years and 25% (130) were aged less than 4 years. The most common cleft type in our study was bilateral cleft palate. The most commonly associated anomaly among cleft patients, in 12% of cleft patients, was a cardiac anomaly. The most common cardiac anomaly was atrial septal defect (ASD).   Conclusion:  The prevalence of associated anomalies among orofacial cleft patients is high. The most common associated anomaly is cardiac anomaly, with ASD being the most common cardiac anomaly. There are no significant relationships between type of cleft and associated cardiac anomalies.http://ijorl.mums.ac.ir/article_6544_3cbb4f7d2774af11e047afb916a7b36c.pdfAnomalyCardiacCleftOro-facial
collection DOAJ
language English
format Article
sources DOAJ
author Shahin Abdollahi Fakhim
Nikzad Shahidi
Alireza Lotfi
spellingShingle Shahin Abdollahi Fakhim
Nikzad Shahidi
Alireza Lotfi
Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
Iranian Journal of Otorhinolaryngology
Anomaly
Cardiac
Cleft
Oro-facial
author_facet Shahin Abdollahi Fakhim
Nikzad Shahidi
Alireza Lotfi
author_sort Shahin Abdollahi Fakhim
title Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
title_short Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
title_full Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
title_fullStr Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
title_full_unstemmed Prevalence of Associated Anomalies in Cleft Lip and/or Palate Patients
title_sort prevalence of associated anomalies in cleft lip and/or palate patients
publisher Mashhad University of Medical Sciences
series Iranian Journal of Otorhinolaryngology
issn 2251-7251
2251-726X
publishDate 2016-03-01
description Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnostic procedure used. In this study we determined the prevalence of associated anomalies in patients with a cleft lip and/or palate, with a specific focus on cardiac anomalies. Materials and Methods: In this cross-sectional study, 526 patients with a cleft lip and /or palate admitted to the children’s referral hospital between 2006 and 2011 were evaluated. All associated anomalies were detected and recorded. Patient information collected included age, gender, type and side of cleft, craniofacial anomalies and presence of other anomalies, including cardiac anomalies. Data were analyzed using SPSS version 16.   Results: Of the 526 patients enrolled in the study, 58% (305) were male and 42% (221) were female. In total, 75% of patients (396) were aged between 4 and 8 years and 25% (130) were aged less than 4 years. The most common cleft type in our study was bilateral cleft palate. The most commonly associated anomaly among cleft patients, in 12% of cleft patients, was a cardiac anomaly. The most common cardiac anomaly was atrial septal defect (ASD).   Conclusion:  The prevalence of associated anomalies among orofacial cleft patients is high. The most common associated anomaly is cardiac anomaly, with ASD being the most common cardiac anomaly. There are no significant relationships between type of cleft and associated cardiac anomalies.
topic Anomaly
Cardiac
Cleft
Oro-facial
url http://ijorl.mums.ac.ir/article_6544_3cbb4f7d2774af11e047afb916a7b36c.pdf
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