Brentuximab vedotin in children and adolescents with Hodgkin’s lymphoma and anaplastic large cell lymphoma – literature review and own experience

Despite significant advances in the treatment of lymphomas in children remain a small proportion of patients with refractory or recurrent disease. An effective approach to the treatment of such patients – not only is the second line chemotherapy, but the use of the new targeted therapies. An example...

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Bibliographic Details
Main Authors: N. V. Myakova, D. A. Evstratov, D. S. Abramov, D. M. Konovalov, A. V. Pshonkin, D. V. Litvinov
Format: Article
Language:Russian
Published: ABV-press 2016-03-01
Series:Onkogematologiâ
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/176
Description
Summary:Despite significant advances in the treatment of lymphomas in children remain a small proportion of patients with refractory or recurrent disease. An effective approach to the treatment of such patients – not only is the second line chemotherapy, but the use of the new targeted therapies. An example of this approach is the use of brentuximab vedotin (antibody-drug conjugate directed to the CD30) in relapsed Hodgkin’s lymphoma and anaplastic large cell lymphoma. Literature review and own experience of using this drug in children are describes in this article.
ISSN:1818-8346