Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa

Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa

Nuclear receptors (NRs) are transcription factors accomplishing a multiplicity of functions, essential for organismal homeostasis. Among their numerous members, the retinoid X receptor (RXR) is a central player of the endocrine system, with a singular ability to operate as a homodimer or a heterodim...

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Bibliographic Details
Main Authors: Elza Fonseca, Raquel Ruivo, Débora Borges, João N. Franco, Miguel M. Santos, L. Filipe C. Castro
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
retinoid X receptor
metazoa
Bryozoa
endocrine disruption
9-cis retinoic acid
TBT
Online Access:https://www.mdpi.com/2218-273X/10/4/594

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