Unexpected Modulation of Recall B and T Cell Responses after Immunization with Rotavirus-like Particles in the Presence of LT-R192G

Unexpected Modulation of Recall B and T Cell Responses after Immunization with Rotavirus-like Particles in the Presence of LT-R192G

LT-R192G, a mutant of the thermolabile enterotoxin of E. coli, is a potent adjuvant of immunization. Immune responses are generally analyzed at the end of protocols including at least 2 administrations, but rarely after a prime. To investigate this point, we compared B and T cell responses in mice a...

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Bibliographic Details
Main Authors: Christelle Basset, John D. Clements, Didier Poncet, Claire Cachia, Annie Charpilienne, Fabienne Bon, Cyrille Di Martino, Fatou Thiam, Evelyne Kohli
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Toxins
Subjects:
LT-R192G
Foxp3
CD25
regulatory T cells
B lymphocyte
B-1a lymphocyte
mucosal immunization
rotavirus
Online Access:http://www.mdpi.com/2072-6651/2/8/2007/

Internet

http://www.mdpi.com/2072-6651/2/8/2007/

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