Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling

Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling

Pulmonary arterial hypertension (PAH) is a progressive disease which causes right ventricular (RV) failure. Canstatin, a C-terminal fragment of type IV collagen α2 chain, is expressed in various rat organs. However, the expression level of canstatin in plasma and organs during PAH is still unclear....

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Bibliographic Details
Main Authors: Akira Sugiyama, Maina Kaisho, Muneyoshi Okada, Kosuke Otani, Hideyuki Yamawaki
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
canstatin
ELISA
fibrosis
hypertrophy
pulmonary arterial hypertension
Online Access:https://www.mdpi.com/1422-0067/21/18/6797

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