Foscarnet-induced genital lesions: An overview with a case report
Foscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990’s, genital ulcers are a potential side effect in about 10% of cases. We report the case of a 29 year old man with acute mye...
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doaj-3952ad452e044c8583b247bbff5fa8762020-11-25T03:55:54ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062018-06-0110110.4081/dr.2018.77493954Foscarnet-induced genital lesions: An overview with a case reportJonas A. Adalsteinsson0Michael Pan1Shivani Kaushik2Jonathan Ungar3Department of Dermatology, Mount Sinai, New York City, NYDepartment of Dermatology, Mount Sinai, New York City, NYDepartment of Dermatology, Mount Sinai, New York City, NYDepartment of Dermatology, Mount Sinai, New York City, NYFoscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990’s, genital ulcers are a potential side effect in about 10% of cases. We report the case of a 29 year old man with acute myelogenous leukemia who was on ganciclovir for CMV prophylaxis. Three weeks after being switched to foscarnet because of neutropenia, he developed two, painful symmetric ulcers on the inferior aspect of glans penis. Viral and bacterial cultures were negative. Two weeks after stopping the infusion of foscarnet, the ulcers subsided without any additional treatment. It is important that physicians be aware of this potentially disfiguring side effect of foscarnet so that methods of prevention can be implemented early in the treatment of these patients.https://www.pagepress.org/journals/index.php/dr/article/view/7749Foscarnetulcergenital. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jonas A. Adalsteinsson Michael Pan Shivani Kaushik Jonathan Ungar |
spellingShingle |
Jonas A. Adalsteinsson Michael Pan Shivani Kaushik Jonathan Ungar Foscarnet-induced genital lesions: An overview with a case report Dermatology Reports Foscarnet ulcer genital. |
author_facet |
Jonas A. Adalsteinsson Michael Pan Shivani Kaushik Jonathan Ungar |
author_sort |
Jonas A. Adalsteinsson |
title |
Foscarnet-induced genital lesions: An overview with a case report |
title_short |
Foscarnet-induced genital lesions: An overview with a case report |
title_full |
Foscarnet-induced genital lesions: An overview with a case report |
title_fullStr |
Foscarnet-induced genital lesions: An overview with a case report |
title_full_unstemmed |
Foscarnet-induced genital lesions: An overview with a case report |
title_sort |
foscarnet-induced genital lesions: an overview with a case report |
publisher |
PAGEPress Publications |
series |
Dermatology Reports |
issn |
2036-7392 2036-7406 |
publishDate |
2018-06-01 |
description |
Foscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990’s, genital ulcers are a potential side effect in about 10% of cases. We report the case of a 29 year old man with acute myelogenous leukemia who was on ganciclovir for CMV prophylaxis. Three weeks after being switched to foscarnet because of neutropenia, he developed two, painful symmetric ulcers on the inferior aspect of glans penis. Viral and bacterial cultures were negative. Two weeks after stopping the infusion of foscarnet, the ulcers subsided without any additional treatment. It is important that physicians be aware of this potentially disfiguring side effect of foscarnet so that methods of prevention can be implemented early in the treatment of these patients. |
topic |
Foscarnet ulcer genital. |
url |
https://www.pagepress.org/journals/index.php/dr/article/view/7749 |
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