The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging

Objective: Islets secrete neurotransmitters including glutamate which participate in fine regulation of islet function. The excitatory ionotropic glutamate receptor GluK2 of the kainate receptor family is widely expressed in brain and also found in islets, mainly in α and γ cells. α cells co-release...

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Bibliographic Details
Main Authors: Myriam Abarkan, Julien Gaitan, Fanny Lebreton, Romain Perrier, Manon Jaffredo, Christophe Mulle, Christophe Magnan, Matthieu Raoux, Jochen Lang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309147