The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry
Objective: to study the clinical characteristics of PsA and working capacity in patients included in the All-Russian PsA Registry.Patients and methods. The investigation enrolled 614 patients aged 19–84 years with psoriasis from 39 subjects the Russian Federation, who were followed up in the All-Rus...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
IMA-PRESS LLC
2020-09-01
|
Series: | Современная ревматология |
Subjects: | |
Online Access: | https://mrj.ima-press.net/mrj/article/view/1040 |
id |
doaj-3983e5a5d03c41408a2c61e3cff76c94 |
---|---|
record_format |
Article |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
E. Yu. Loginova T. V. Korotaeva Yu. L. Korsakova E. E. Gubar P. O. Tremaskina E. A. Vasilenko I. N. Kushnir I. M. Patkikeeva S. S. Kudishina P. A. Shesternya A. V. Petrov N. A. Kuznetsova E. L. Nasonov |
spellingShingle |
E. Yu. Loginova T. V. Korotaeva Yu. L. Korsakova E. E. Gubar P. O. Tremaskina E. A. Vasilenko I. N. Kushnir I. M. Patkikeeva S. S. Kudishina P. A. Shesternya A. V. Petrov N. A. Kuznetsova E. L. Nasonov The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry Современная ревматология psoriatic arthritis registry functional impairment quality of life working capacity absenteeism presenteeism |
author_facet |
E. Yu. Loginova T. V. Korotaeva Yu. L. Korsakova E. E. Gubar P. O. Tremaskina E. A. Vasilenko I. N. Kushnir I. M. Patkikeeva S. S. Kudishina P. A. Shesternya A. V. Petrov N. A. Kuznetsova E. L. Nasonov |
author_sort |
E. Yu. Loginova |
title |
The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry |
title_short |
The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry |
title_full |
The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry |
title_fullStr |
The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry |
title_full_unstemmed |
The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis Registry |
title_sort |
clinical status and working capacity in patients included in the all-russian psoriatic arthritis registry |
publisher |
IMA-PRESS LLC |
series |
Современная ревматология |
issn |
1996-7012 2310-158X |
publishDate |
2020-09-01 |
description |
Objective: to study the clinical characteristics of PsA and working capacity in patients included in the All-Russian PsA Registry.Patients and methods. The investigation enrolled 614 patients aged 19–84 years with psoriasis from 39 subjects the Russian Federation, who were followed up in the All-Russian PsA Registry. On the basis of the assessment of demographic data, the spectrum of comorbidities, the degree of activity of the underlying disease according to Disease Activity Index for PsA (DAPSA) and Disease Activity in 28 joints (DAS28), clinical, functional, and social indicators were analyzed in the patients. The investigators studied information on the patients employment, working capacity, and disability, by assessing the group of the latter. The health status and the presence and severity of functional impairment in the patients were analyzed using the Health Assessment Questionnaire (HAQ), while their working efficiency was estimated according to the Workers Productivity and Activity Impairment Questionnaire: Specific Health Problem (WPAI-SHP questionnaire), by calculating the following parameters: absenteeism, presenteeism, an overall decrease in labor productivity, and impairment in daily functional activity.Results and discussion. The analysis of the All-Russian PsA Registry showed that most of them were of working age (30 to 59 years); 48.4% had concomitant diseases. Data on DAPSA changes were obtained in 349 patients, who were recorded to have mainly moderate (34.7%) or high (42.7%) disease activity, multiple dactylitides and enthesitides, and limited joint function. The registry reflects information on the social status of 521 patients: employed (61.2%) and unemployed (22.1%) persons, pensioners (15.2%), and students (1.5%). More than one third (37.1%) of patients with PsA had disability, mainly of Group III. The changes in the HAQ disability index were assessed in 326 patients; mild, moderate, and severe functional impairments were observed in 36, 26.4, and 3.7%, respectively. Absenteeism was detected in less than one third of patients with PsA, presenteeism was found in about half; there was an overall decrease in labor productivity in more than 60% and daily activity impairment in 68.8%. Statistically significant direct moderate correlations were established between the indicators of PsA activity (DAPSA and DAS28) and the level of productivity impairment in the patients; this was mostly related to an overall decline in labor productivity and to a decrease in daily activity.Conclusion. The data obtained from real clinical practice suggest that half of the PsA patients had high disease activity and a third had severe functional impairment, which led to a lower quality of life and to disability. The overall decrease in labor productivity and daily activity, which was detected in more than half of the patients, was associated with high PsA activity. The follow-up in the All-Russian PsA Registry, regular anti-inflammatory therapy with disease-modifying antirheumatic drugs and biological agents can improve the clinical and functional status and, consequently, working capacity in patients with PsA. |
topic |
psoriatic arthritis registry functional impairment quality of life working capacity absenteeism presenteeism |
url |
https://mrj.ima-press.net/mrj/article/view/1040 |
work_keys_str_mv |
AT eyuloginova theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT tvkorotaeva theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT yulkorsakova theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT eegubar theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT potremaskina theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT eavasilenko theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT inkushnir theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT impatkikeeva theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT sskudishina theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT pashesternya theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT avpetrov theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT nakuznetsova theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT elnasonov theclinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT eyuloginova clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT tvkorotaeva clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT yulkorsakova clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT eegubar clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT potremaskina clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT eavasilenko clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT inkushnir clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT impatkikeeva clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT sskudishina clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT pashesternya clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT avpetrov clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT nakuznetsova clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry AT elnasonov clinicalstatusandworkingcapacityinpatientsincludedintheallrussianpsoriaticarthritisregistry |
_version_ |
1721250140120940544 |
spelling |
doaj-3983e5a5d03c41408a2c61e3cff76c942021-07-29T09:00:14ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2020-09-01143192610.14412/1996-7012-2020-3-19-262273The clinical status and working capacity in patients included in the All-Russian Psoriatic Arthritis RegistryE. Yu. Loginova0T. V. Korotaeva1Yu. L. Korsakova2E. E. Gubar3P. O. Tremaskina4E. A. Vasilenko5I. N. Kushnir6I. M. Patkikeeva7S. S. Kudishina8P. A. Shesternya9A. V. Petrov10N. A. Kuznetsova11E. L. Nasonov12V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyI.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaS.V. Belyaev Kemerovo Regional Clinical HospitalTyumen Regional Clinical Hospital OneVladivostok Clinical Hospital TwoProf. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of RussiaN.A. Semashko Republican Clinical HospitalCity Clinical Hospital FortyV.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaObjective: to study the clinical characteristics of PsA and working capacity in patients included in the All-Russian PsA Registry.Patients and methods. The investigation enrolled 614 patients aged 19–84 years with psoriasis from 39 subjects the Russian Federation, who were followed up in the All-Russian PsA Registry. On the basis of the assessment of demographic data, the spectrum of comorbidities, the degree of activity of the underlying disease according to Disease Activity Index for PsA (DAPSA) and Disease Activity in 28 joints (DAS28), clinical, functional, and social indicators were analyzed in the patients. The investigators studied information on the patients employment, working capacity, and disability, by assessing the group of the latter. The health status and the presence and severity of functional impairment in the patients were analyzed using the Health Assessment Questionnaire (HAQ), while their working efficiency was estimated according to the Workers Productivity and Activity Impairment Questionnaire: Specific Health Problem (WPAI-SHP questionnaire), by calculating the following parameters: absenteeism, presenteeism, an overall decrease in labor productivity, and impairment in daily functional activity.Results and discussion. The analysis of the All-Russian PsA Registry showed that most of them were of working age (30 to 59 years); 48.4% had concomitant diseases. Data on DAPSA changes were obtained in 349 patients, who were recorded to have mainly moderate (34.7%) or high (42.7%) disease activity, multiple dactylitides and enthesitides, and limited joint function. The registry reflects information on the social status of 521 patients: employed (61.2%) and unemployed (22.1%) persons, pensioners (15.2%), and students (1.5%). More than one third (37.1%) of patients with PsA had disability, mainly of Group III. The changes in the HAQ disability index were assessed in 326 patients; mild, moderate, and severe functional impairments were observed in 36, 26.4, and 3.7%, respectively. Absenteeism was detected in less than one third of patients with PsA, presenteeism was found in about half; there was an overall decrease in labor productivity in more than 60% and daily activity impairment in 68.8%. Statistically significant direct moderate correlations were established between the indicators of PsA activity (DAPSA and DAS28) and the level of productivity impairment in the patients; this was mostly related to an overall decline in labor productivity and to a decrease in daily activity.Conclusion. The data obtained from real clinical practice suggest that half of the PsA patients had high disease activity and a third had severe functional impairment, which led to a lower quality of life and to disability. The overall decrease in labor productivity and daily activity, which was detected in more than half of the patients, was associated with high PsA activity. The follow-up in the All-Russian PsA Registry, regular anti-inflammatory therapy with disease-modifying antirheumatic drugs and biological agents can improve the clinical and functional status and, consequently, working capacity in patients with PsA.https://mrj.ima-press.net/mrj/article/view/1040psoriatic arthritisregistryfunctional impairmentquality of lifeworking capacityabsenteeismpresenteeism |