Post-myocardial infarction heart failure dysregulates the bone vascular niche

Hematopoiesis influences the progression of cardiovascular disease, yet the influence of cardiovascular disease on the bone vasculature is unknown. Hoffmann, Luxán, Abplanalp et al. describe the response of the bone cell composition to myocardial infarction and provide a rationale for using anti-inf...

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Main Authors: Jedrzej Hoffmann, Guillermo Luxán, Wesley Tyler Abplanalp, Simone-Franziska Glaser, Tina Rasper, Ariane Fischer, Marion Muhly-Reinholz, Michael Potente, Birgit Assmus, David John, Andreas Michael Zeiher, Stefanie Dimmeler
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24045-4
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spelling doaj-398da0beec4046aba06db75788ef5a982021-06-27T11:12:24ZengNature Publishing GroupNature Communications2041-17232021-06-0112111110.1038/s41467-021-24045-4Post-myocardial infarction heart failure dysregulates the bone vascular nicheJedrzej Hoffmann0Guillermo Luxán1Wesley Tyler Abplanalp2Simone-Franziska Glaser3Tina Rasper4Ariane Fischer5Marion Muhly-Reinholz6Michael Potente7Birgit Assmus8David John9Andreas Michael Zeiher10Stefanie Dimmeler11Department of Cardiology, Center of Internal Medicine, Goethe University FrankfurtGerman Center for Cardiovascular Research DZHKGerman Center for Cardiovascular Research DZHKGerman Center for Cardiovascular Research DZHKInstitute of Cardiovascular Regeneration, Center of Molecular Medicine, Goethe University FrankfurtInstitute of Cardiovascular Regeneration, Center of Molecular Medicine, Goethe University FrankfurtInstitute of Cardiovascular Regeneration, Center of Molecular Medicine, Goethe University FrankfurtAngiogenesis and Metabolism Laboratory, Max Planck Institute for Heart and Lung ResearchDepartment of Cardiology, Center of Internal Medicine, Goethe University FrankfurtGerman Center for Cardiovascular Research DZHKDepartment of Cardiology, Center of Internal Medicine, Goethe University FrankfurtGerman Center for Cardiovascular Research DZHKHematopoiesis influences the progression of cardiovascular disease, yet the influence of cardiovascular disease on the bone vasculature is unknown. Hoffmann, Luxán, Abplanalp et al. describe the response of the bone cell composition to myocardial infarction and provide a rationale for using anti-inflammatory therapies to prevent the deterioration of the bone vascular nichehttps://doi.org/10.1038/s41467-021-24045-4
collection DOAJ
language English
format Article
sources DOAJ
author Jedrzej Hoffmann
Guillermo Luxán
Wesley Tyler Abplanalp
Simone-Franziska Glaser
Tina Rasper
Ariane Fischer
Marion Muhly-Reinholz
Michael Potente
Birgit Assmus
David John
Andreas Michael Zeiher
Stefanie Dimmeler
spellingShingle Jedrzej Hoffmann
Guillermo Luxán
Wesley Tyler Abplanalp
Simone-Franziska Glaser
Tina Rasper
Ariane Fischer
Marion Muhly-Reinholz
Michael Potente
Birgit Assmus
David John
Andreas Michael Zeiher
Stefanie Dimmeler
Post-myocardial infarction heart failure dysregulates the bone vascular niche
Nature Communications
author_facet Jedrzej Hoffmann
Guillermo Luxán
Wesley Tyler Abplanalp
Simone-Franziska Glaser
Tina Rasper
Ariane Fischer
Marion Muhly-Reinholz
Michael Potente
Birgit Assmus
David John
Andreas Michael Zeiher
Stefanie Dimmeler
author_sort Jedrzej Hoffmann
title Post-myocardial infarction heart failure dysregulates the bone vascular niche
title_short Post-myocardial infarction heart failure dysregulates the bone vascular niche
title_full Post-myocardial infarction heart failure dysregulates the bone vascular niche
title_fullStr Post-myocardial infarction heart failure dysregulates the bone vascular niche
title_full_unstemmed Post-myocardial infarction heart failure dysregulates the bone vascular niche
title_sort post-myocardial infarction heart failure dysregulates the bone vascular niche
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-06-01
description Hematopoiesis influences the progression of cardiovascular disease, yet the influence of cardiovascular disease on the bone vasculature is unknown. Hoffmann, Luxán, Abplanalp et al. describe the response of the bone cell composition to myocardial infarction and provide a rationale for using anti-inflammatory therapies to prevent the deterioration of the bone vascular niche
url https://doi.org/10.1038/s41467-021-24045-4
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