Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery
Background: Hidradenitis suppurativa (HS) is an inflammatory and chronic-recurrent disease of the hair follicle. Its aetiopathogenesis is not completely known. Although bacterial colonization and superinfection are clinically relevant, lymph node involvement has rarely been studied. Objectives: In t...
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doaj-39994c0f7f1a42568d5f01784cabb8cc2021-04-01T23:06:59ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01101433143310.3390/jcm10071433Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical SurgerySilvia Vaienti0Gianluca Nazzaro1Anna Grancini2Paolo Calzari3Giovanna Zaccaria4Stefano Veraldi5Luca Vaienti6Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, ItalyMicrobiology Laboratory, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Via San Barnaba 8, 20122 Milan, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, ItalyDivision of Plastic Surgery, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, ItalyDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, IRCCS Policlinico San Donato, Piazza Edmondo Malan 1, San Donato Milanese, 20097 Milan, ItalyBackground: Hidradenitis suppurativa (HS) is an inflammatory and chronic-recurrent disease of the hair follicle. Its aetiopathogenesis is not completely known. Although bacterial colonization and superinfection are clinically relevant, lymph node involvement has rarely been studied. Objectives: In this pilot retrospective study, we evaluated the clinical and microbiological nodal involvement in patients with axillary hidradenitis suppurativa. Materials and methods: We retrospectively analyzed patients suffering from axillary hidradenitis suppurativa and referred to the Dermatology Unit of the Foundation Ca’ Granda Ospedale Maggiore Policlinico in Milan between October 2018 and November 2019. The sampling procedure took place during the surgical excision of lesions at the Operative Unit of Plastic and Reconstructive Surgery of Policlinico San Donato Hospital. Three types of sample were sent to microbiological analysis: exudate swab, axillary lymph node, fistula. Result: In total, we recruited 10 patients. Two of them underwent bilateral axillary surgery. Nine lymph nodes were analyzed. In one patient, bacterial culture in lymph nodes, skin lesions and fistulae matched. Conclusions: Unequivocable conclusions cannot be drawn due to the low number of patients. Further studies are necessary to confirm the preliminary results of our retrospective pilot study.https://www.mdpi.com/2077-0383/10/7/1433hidradenitis suppurativalymph nodeultrasoundmicrobiologyplastic surgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Silvia Vaienti Gianluca Nazzaro Anna Grancini Paolo Calzari Giovanna Zaccaria Stefano Veraldi Luca Vaienti |
spellingShingle |
Silvia Vaienti Gianluca Nazzaro Anna Grancini Paolo Calzari Giovanna Zaccaria Stefano Veraldi Luca Vaienti Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery Journal of Clinical Medicine hidradenitis suppurativa lymph node ultrasound microbiology plastic surgery |
author_facet |
Silvia Vaienti Gianluca Nazzaro Anna Grancini Paolo Calzari Giovanna Zaccaria Stefano Veraldi Luca Vaienti |
author_sort |
Silvia Vaienti |
title |
Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery |
title_short |
Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery |
title_full |
Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery |
title_fullStr |
Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery |
title_full_unstemmed |
Lymph Node Involvement in Axillary Hidradenitis Suppurativa: A Clinical, Ultrasonographic and Bacteriological Study Conducted during Radical Surgery |
title_sort |
lymph node involvement in axillary hidradenitis suppurativa: a clinical, ultrasonographic and bacteriological study conducted during radical surgery |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2021-04-01 |
description |
Background: Hidradenitis suppurativa (HS) is an inflammatory and chronic-recurrent disease of the hair follicle. Its aetiopathogenesis is not completely known. Although bacterial colonization and superinfection are clinically relevant, lymph node involvement has rarely been studied. Objectives: In this pilot retrospective study, we evaluated the clinical and microbiological nodal involvement in patients with axillary hidradenitis suppurativa. Materials and methods: We retrospectively analyzed patients suffering from axillary hidradenitis suppurativa and referred to the Dermatology Unit of the Foundation Ca’ Granda Ospedale Maggiore Policlinico in Milan between October 2018 and November 2019. The sampling procedure took place during the surgical excision of lesions at the Operative Unit of Plastic and Reconstructive Surgery of Policlinico San Donato Hospital. Three types of sample were sent to microbiological analysis: exudate swab, axillary lymph node, fistula. Result: In total, we recruited 10 patients. Two of them underwent bilateral axillary surgery. Nine lymph nodes were analyzed. In one patient, bacterial culture in lymph nodes, skin lesions and fistulae matched. Conclusions: Unequivocable conclusions cannot be drawn due to the low number of patients. Further studies are necessary to confirm the preliminary results of our retrospective pilot study. |
topic |
hidradenitis suppurativa lymph node ultrasound microbiology plastic surgery |
url |
https://www.mdpi.com/2077-0383/10/7/1433 |
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