Molecular Features and Metal Ions that Influence 10-23 DNAzyme Activity
Deoxyribozymes (DNAzymes) with RNA hydrolysis activity have a tremendous potential as gene suppression agents for therapeutic applications. The most extensively studied representative is the 10-23 DNAzyme consisting of a catalytic loop and two substrate binding arms that can be designed to bind and...
Main Authors: | Hannah Rosenbach, Julian Victor, Manuel Etzkorn, Gerhard Steger, Detlev Riesner, Ingrid Span |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/13/3100 |
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