Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan

Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan

Bibliographic Details
Main Authors: Peichuan Zhang, Yuying Zhai, James Cregg, Kenny Kean-Hooi Ang, Michelle Arkin, Cynthia Kenyon
Format: Article
Language:English
Published: Oxford University Press 2020-02-01
Series:G3: Genes, Genomes, Genetics
Subjects:
small molecule screen
oxidative stress
stress resistance
nrf2
aging
c. elegans
wi-38
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400618
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spelling doaj-39e0b6cd6f2646268a3528c3b8c7ec9b2021-07-02T08:00:55ZengOxford University PressG3: Genes, Genomes, Genetics2160-18362020-02-0110284986210.1534/g3.119.40061837Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ LifespanPeichuan ZhangYuying ZhaiJames CreggKenny Kean-Hooi AngMichelle ArkinCynthia Kenyonhttp://g3journal.org/lookup/doi/10.1534/g3.119.400618small molecule screenoxidative stressstress resistancenrf2agingc. eleganswi-38
collection DOAJ
language English
format Article
sources DOAJ
author Peichuan Zhang
Yuying Zhai
James Cregg
Kenny Kean-Hooi Ang
Michelle Arkin
Cynthia Kenyon
spellingShingle Peichuan Zhang
Yuying Zhai
James Cregg
Kenny Kean-Hooi Ang
Michelle Arkin
Cynthia Kenyon
Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
G3: Genes, Genomes, Genetics
small molecule screen
oxidative stress
stress resistance
nrf2
aging
c. elegans
wi-38
author_facet Peichuan Zhang
Yuying Zhai
James Cregg
Kenny Kean-Hooi Ang
Michelle Arkin
Cynthia Kenyon
author_sort Peichuan Zhang
title Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
title_short Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
title_full Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
title_fullStr Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
title_full_unstemmed Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
title_sort stress resistance screen in a human primary cell line identifies small molecules that affect aging pathways and extend caenorhabditis elegans’ lifespan
publisher Oxford University Press
series G3: Genes, Genomes, Genetics
issn 2160-1836
publishDate 2020-02-01
topic small molecule screen
oxidative stress
stress resistance
nrf2
aging
c. elegans
wi-38
url http://g3journal.org/lookup/doi/10.1534/g3.119.400618
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AT yuyingzhai stressresistancescreeninahumanprimarycelllineidentifiessmallmoleculesthataffectagingpathwaysandextendcaenorhabditiseleganslifespan
AT jamescregg stressresistancescreeninahumanprimarycelllineidentifiessmallmoleculesthataffectagingpathwaysandextendcaenorhabditiseleganslifespan
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