Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature
Abstract Background Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has b...
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doaj-39fcde3480b54bd68d5a10a7118854852020-11-25T03:38:18ZengBMCBMC Infectious Diseases1471-23342018-08-011811510.1186/s12879-018-3284-5Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literatureKiwamu Nakamura0Kyoichi Saito1Yasuka Hara2Tetsuji Aoyagi3Kadzuhiro Kitakawa4Yoshinobu Abe5Hiromu Takemura6Fumihito Ikeda7Mitsuo Kaku8Keiji Kanemitsu9Department of Infection Control, Fukushima Medical UniversityDepartment of Infection Control, Fukushima Medical UniversityDepartment of Infection Control, Fukushima Medical UniversityDepartment of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of MedicineDepartment of Microbiology, Fukushima Prefectural Institute of Public HealthDepartment of Infection Control, Fukushima Medical UniversityDepartment of Microbiology, St. Marianna University School of MedicineIkeda Memorial HospitalDepartment of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of MedicineDepartment of Infection Control, Fukushima Medical UniversityAbstract Background Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has been linked to epidemic myalgia, regardless of the presence of underlying diseases, immunosuppression, or sex. Case presentation We describe an adult case of severe systemic myalgia and orchiodynia after infection with HPeV-3, which was transmitted from the child of the patient. Interleukin-6 (IL-6) level was found to be elevated in the patient’s serum. Conclusion Severe myalgia associated with HPeV-3 infection is potentially caused by an elevated serum level of IL-6.http://link.springer.com/article/10.1186/s12879-018-3284-5Human parechovirus type 3Epidemic myalgiaOrchiodyniaIL-6 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kiwamu Nakamura Kyoichi Saito Yasuka Hara Tetsuji Aoyagi Kadzuhiro Kitakawa Yoshinobu Abe Hiromu Takemura Fumihito Ikeda Mitsuo Kaku Keiji Kanemitsu |
spellingShingle |
Kiwamu Nakamura Kyoichi Saito Yasuka Hara Tetsuji Aoyagi Kadzuhiro Kitakawa Yoshinobu Abe Hiromu Takemura Fumihito Ikeda Mitsuo Kaku Keiji Kanemitsu Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature BMC Infectious Diseases Human parechovirus type 3 Epidemic myalgia Orchiodynia IL-6 |
author_facet |
Kiwamu Nakamura Kyoichi Saito Yasuka Hara Tetsuji Aoyagi Kadzuhiro Kitakawa Yoshinobu Abe Hiromu Takemura Fumihito Ikeda Mitsuo Kaku Keiji Kanemitsu |
author_sort |
Kiwamu Nakamura |
title |
Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature |
title_short |
Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature |
title_full |
Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature |
title_fullStr |
Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature |
title_full_unstemmed |
Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature |
title_sort |
severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature |
publisher |
BMC |
series |
BMC Infectious Diseases |
issn |
1471-2334 |
publishDate |
2018-08-01 |
description |
Abstract Background Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has been linked to epidemic myalgia, regardless of the presence of underlying diseases, immunosuppression, or sex. Case presentation We describe an adult case of severe systemic myalgia and orchiodynia after infection with HPeV-3, which was transmitted from the child of the patient. Interleukin-6 (IL-6) level was found to be elevated in the patient’s serum. Conclusion Severe myalgia associated with HPeV-3 infection is potentially caused by an elevated serum level of IL-6. |
topic |
Human parechovirus type 3 Epidemic myalgia Orchiodynia IL-6 |
url |
http://link.springer.com/article/10.1186/s12879-018-3284-5 |
work_keys_str_mv |
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