Regenerating hair cells in vestibular sensory epithelia from humans
Human vestibular sensory epithelia in explant culture were incubated in gentamicin to ablate hair cells. Subsequent transduction of supporting cells with ATOH1 using an Ad-2 viral vector resulted in generation of highly significant numbers of cells expressing the hair cell marker protein myosin VIIa...
Main Authors: | Ruth Rebecca Taylor, Anastasia Filia, Ursula Paredes, Yukako Asai, Jeffrey R Holt, Michael Lovett, Andrew Forge |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-07-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/34817 |
Similar Items
-
Hair cell regeneration in vestibular epithelia : a study in an in vitro model
by: Werner, Mimmi
Published: (2016) -
Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1
by: Hsin-I Jen, et al.
Published: (2019-04-01) -
Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice
by: Stephanie A Bucks, et al.
Published: (2017-03-01) -
Analysis of Vestibular Hair Cell Bundle Mechanics Using Finite Element Modeling
by: Silber, Joseph Allan
Published: (2011) -
Experimental Measurements of Vestibular Hair Bundle Stiffness in the Red Ear Slider Turtle Utricle
by: Silverman, Jennifer Mary
Published: (2011)