Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial.

Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial.

Artemisinin resistance is threatening global efforts for malaria control and elimination. Primaquine (PQ) and methylene blue (MB) are gametocytocidal drugs that can be combined with artemisinin-based combination therapy (ACT) to reduce malaria transmission, including resistant strains. Children (6-5...

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Bibliographic Details
Main Authors: Margarida Mendes Jorge, Lucienne Ouermi, Peter Meissner, Guillaume Compaoré, Boubacar Coulibaly, Eric Nebie, Johannes Krisam, Christina Klose, Meinhard Kieser, Albrecht Jahn, Guangyu Lu, Umberto D Alessandro, Ali Sié, Frank Peter Mockenhaupt, Olaf Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222993

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https://doi.org/10.1371/journal.pone.0222993

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