Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study
<b>Background:</b> The establishment and maintenance of oral microbiota is related not only to interbacterial coaggregations but also to interactions of these bacteria with yeasts<i>.</i> Hence, it is important for agents used in the treatment of oral diseases to have antifun...
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doaj-3a200d938c27416fa29e39abaf3b57612020-11-24T21:07:00ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032010-01-01213334336Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> studyPai MithunPrashant GMurlikrishna KShivakumar KChandu G<b>Background:</b> The establishment and maintenance of oral microbiota is related not only to interbacterial coaggregations but also to interactions of these bacteria with yeasts<i>.</i> Hence, it is important for agents used in the treatment of oral diseases to have antifungal properties for effective therapy. <b>Objective:</b> The main purpose of this study was to evaluate the <i>in vitro</i> antifungal efficacy of <i>Punica granatum, Acacia nilotica, Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans.</i> <b>Materials and Methods:</b> The pomegranate peel is separated, dried and powdered. Fennel, cumin and acacia bark obtained from the tree are powdered. Candida is inoculated at 37˚C and seeded on Sabourauds agar medium. Sterilized filter papers saturated with 30 μl of the extracts are placed on the seeded plates and inoculated at 24 and 48 h. Zones of inhibition on all four sides are measured around the filter paper with a vernier caliper. The experiments were repeated on four plates, with four samples of each extract on one plate for all of the extracts. <b>Results:</b> All the above-mentioned ingredients showed antifungal property, with <i>Punica granatum</i> showing the highest inhibition of <i>Candida albicans</i> with a mean zone of inhibition of 22 mm. <i>P</i>-values <0.05 were obtained for <i>Punica granatum</i> when compared with the other extracts. <b>Conclusion:</b> The results showed the potential use of these products as cheap and convenient adjuvants to pharmaceutical antifungal products.http://www.ijdr.in/article.asp?issn=0970-9290;year=2010;volume=21;issue=3;spage=334;epage=336;aulast=PaiAntifungal properbabulcandidacuminfennelpomegranate |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pai Mithun Prashant G Murlikrishna K Shivakumar K Chandu G |
spellingShingle |
Pai Mithun Prashant G Murlikrishna K Shivakumar K Chandu G Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study Indian Journal of Dental Research Antifungal proper babul candida cumin fennel pomegranate |
author_facet |
Pai Mithun Prashant G Murlikrishna K Shivakumar K Chandu G |
author_sort |
Pai Mithun |
title |
Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study |
title_short |
Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study |
title_full |
Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study |
title_fullStr |
Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study |
title_full_unstemmed |
Antifungal efficacy of <i>Punica granatum</i>, <i>Acacia nilotica</i>, <i>Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans</i>: An <i>in vitro</i> study |
title_sort |
antifungal efficacy of <i>punica granatum</i>, <i>acacia nilotica</i>, <i>cuminum cyminum</i> and <i>foeniculum vulgare</i> on <i>candida albicans</i>: an <i>in vitro</i> study |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Dental Research |
issn |
0970-9290 1998-3603 |
publishDate |
2010-01-01 |
description |
<b>Background:</b> The establishment and maintenance of oral microbiota is related not only to interbacterial coaggregations but also to interactions of these bacteria with yeasts<i>.</i> Hence, it is important for agents used in the treatment of oral diseases to have antifungal properties for effective therapy. <b>Objective:</b> The main purpose of this study was to evaluate the <i>in vitro</i> antifungal efficacy of <i>Punica granatum, Acacia nilotica, Cuminum cyminum</i> and <i>Foeniculum vulgare</i> on <i>Candida albicans.</i> <b>Materials and Methods:</b> The pomegranate peel is separated, dried and powdered. Fennel, cumin and acacia bark obtained from the tree are powdered. Candida is inoculated at 37˚C and seeded on Sabourauds agar medium. Sterilized filter papers saturated with 30 μl of the extracts are placed on the seeded plates and inoculated at 24 and 48 h. Zones of inhibition on all four sides are measured around the filter paper with a vernier caliper. The experiments were repeated on four plates, with four samples of each extract on one plate for all of the extracts. <b>Results:</b> All the above-mentioned ingredients showed antifungal property, with <i>Punica granatum</i> showing the highest inhibition of <i>Candida albicans</i> with a mean zone of inhibition of 22 mm. <i>P</i>-values <0.05 were obtained for <i>Punica granatum</i> when compared with the other extracts. <b>Conclusion:</b> The results showed the potential use of these products as cheap and convenient adjuvants to pharmaceutical antifungal products. |
topic |
Antifungal proper babul candida cumin fennel pomegranate |
url |
http://www.ijdr.in/article.asp?issn=0970-9290;year=2010;volume=21;issue=3;spage=334;epage=336;aulast=Pai |
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