Next generation shotgun sequencing and the challenges of de novo genome assembly

Next generation shotgun sequencing and the challenges of de novo genome assembly

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Sequencing the genomes of the many scientifically fascinating plants and animals found in South Africa is fast becoming a viable option as a result of the rapid and sustained drop in the cost of next generation sequencing over the last five years. However, the processing and assembly of the sequenc...

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Bibliographic Details
Main Authors: Stephen Schlebusch, Nicola Illing
Format: Article
Language:English
Published: Academy of Science of South Africa 2012-10-01
Series:South African Journal of Science
Subjects:
de novo genome assembly
next generation sequencing
de Bruijn
whole genome sequencing
Online Access:http://192.168.0.108/index.php/sajs/article/view/9649
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