Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway

Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway

Oxidative stress is a common feature of neurodegenerative diseases and plays an important role in disease progression. Appoptosin is a pro-apoptotic protein that contributes to the pathogenesis of neurodegenerative diseases such as Alzheimer's disease and progressive supranuclear palsy. However...

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Bibliographic Details
Main Authors: Cuilin Zhang, Zhenqiu Tan, Yongzhuang Xie, Yingjun Zhao, Timothy Y. Huang, Zhaoping Lu, Hong Luo, Dan Can, Huaxi Xu, Yun-wu Zhang, Xian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
appoptosin
oxidative stress
ROS
JNK
FoxO1
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00243/full

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