Cisplatin cytotoxicity is dependent on mitochondrial respiration in Saccharomyces cerevisiae

Cisplatin cytotoxicity is dependent on mitochondrial respiration in Saccharomyces cerevisiae

Objective(s): To understand the role of mitochondrial respiration in cisplatin sensitivity, we have employed wild-type and mitochondrial DNA depleted Rho0 yeast cells. Materials and Methods: Wild type and Rho0 yeast cultured in fermentable and non-fermentable sugar containing media, were studied for...

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Bibliographic Details
Main Authors: Santhipriya Inapurapu, Karunakar Rao Kudle, Sreedhar Bodiga, Vijaya Lakshmi Bodiga
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Cisplatin
Mitochondria
Oxidative phosphorylation Respiration
Rho0
Online Access:http://ijbms.mums.ac.ir/article_8099_8b06620bd9c5ce2cb77c6385af337637.pdf

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