Gap Junctional Communication via Connexin43 between Purkinje Fibers and Working Myocytes Explains the Epicardial Activation Pattern in the Postnatal Mouse Left Ventricle

Gap Junctional Communication via Connexin43 between Purkinje Fibers and Working Myocytes Explains the Epicardial Activation Pattern in the Postnatal Mouse Left Ventricle

The mammalian ventricular myocardium forms a functional syncytium due to flow of electrical current mediated in part by gap junctions localized within intercalated disks. The connexin (Cx) subunit of gap junctions have direct and indirect roles in conduction of electrical impulse from the cardiac pa...

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Bibliographic Details
Main Authors: Veronika Olejnickova, Matej Kocka, Alena Kvasilova, Hana Kolesova, Adam Dziacky, Tom Gidor, Lihi Gidor, Barbora Sankova, Martina Gregorovicova, Robert G. Gourdie, David Sedmera
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
connexin
cardiac conduction system
optical mapping
myocardium
immunohistochemistry
Online Access:https://www.mdpi.com/1422-0067/22/5/2475

Internet

https://www.mdpi.com/1422-0067/22/5/2475

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