PDGFR-β-Positive Perivascular Adventitial Cells Expressing Nestin Contribute to Fibrotic Scar Formation in the Striatum of 3-NP Intoxicated Rats

PDGFR-β-Positive Perivascular Adventitial Cells Expressing Nestin Contribute to Fibrotic Scar Formation in the Striatum of 3-NP Intoxicated Rats

Perivascular cells expressing platelet-derived growth factor receptor beta (PDGFR-β) have recently been implicated in fibrotic scar formation after acute brain injury, but their precise identity and detailed morphological characteristics remain elusive. This study sought to characterize and define t...

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Bibliographic Details
Main Authors: Tae-Ryong Riew, Jeong-Heon Choi, Hong Lim Kim, Xuyan Jin, Mun-Yong Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
acute brain injury
brain macrophage
fibrotic scar
nestin
PDGFR-β
perivascular adventitial cell
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00402/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00402/full

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