Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization

Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization

Immunization is key to preventing infectious diseases, a leading cause of death early in life. However, due to age-specific immunity, vaccines often demonstrate reduced efficacy in newborns and young infants as compared to adults. Here, we combined in vitro and in vivo approaches to identify adjuvan...

Full description

Bibliographic Details
Main Authors: Francesco Borriello, Carlo Pietrasanta, Jacqueline C. Y. Lai, Lois M. Walsh, Pankaj Sharma, David N. O’Driscoll, Juan Ramirez, Spencer Brightman, Lorenza Pugni, Fabio Mosca, David J. Burkhart, David J. Dowling, Ofer Levy
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
vaccines
adjuvants
newborn
antigen-presenting cells
germinal centers
T follicular helper cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01772/full

Similar Items

Similar Items