Proteomics Unravels Emodin Causes Liver Oxidative Damage Elicited by Mitochondrial Dysfunction

Proteomics Unravels Emodin Causes Liver Oxidative Damage Elicited by Mitochondrial Dysfunction

Emodin is one of the main active compounds in many Chinese traditional herbs. Due to its potential toxic effect on the liver, the possible injury mechanism needs to be explored. In the present study, we investigated liver injury mechanisms of emodin on rats by the technology of proteomics. Firstly,...

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Bibliographic Details
Main Authors: Yinhuan Zhang, Xiaowei Yang, Zhixin Jia, Jie Liu, Xiaoning Yan, Yihang Dai, Hongbin Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
Emodin
liver injury
proteomics
mitochondrial dysfunction
redox homeostasis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00416/full

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