Transcriptional Profiling the 150 kb Linear Megaplasmid of Borrelia turicatae Suggests a Role in Vector Colonization and Initiating Mammalian Infection.

Transcriptional Profiling the 150 kb Linear Megaplasmid of Borrelia turicatae Suggests a Role in Vector Colonization and Initiating Mammalian Infection.

Adaptation is key for survival as vector-borne pathogens transmit between the arthropod and vertebrate, and temperature change is an environmental signal inducing alterations in gene expression of tick-borne spirochetes. While plasmids are often associated with adaptation, complex genomes of relapsi...

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Bibliographic Details
Main Authors: Hannah K Wilder, Sandra J Raffel, Alan G Barbour, Stephen F Porcella, Daniel E Sturdevant, Benjamin Vaisvil, Vinayak Kapatral, Daniel P Schmitt, Tom G Schwan, Job E Lopez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4741519?pdf=render

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http://europepmc.org/articles/PMC4741519?pdf=render

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