Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy

Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy

Hemophagocytic syndrome (HS) is a rare clinical condition characterized by fever and cytopenia due to phagocytosis of erythrocytes, leukocytes, platelets and their precursors in the bone marrow and other reticuloendothelial systems. The presence of HS can be associated with malignancies, infections...

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Main Authors: Cemal Bes, Uğur Özensoy, Serdar Yanık, Pınar Memedoğlu, Ahsen Zeyrek, Mehmet Soy
Format: Article
Language:English
Published: PAGEPress Publications 2014-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Hemophagocytosis
sulfasalazine
seronegative spondyloarthropathy
Online Access:https://mjhid.org/index.php/mjhid/article/view/1938
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spelling doaj-3a836a772a92463f8dfd4f6272f22eea2020-11-25T03:25:28ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathyCemal Bes0Uğur Özensoy1Serdar Yanık2Pınar Memedoğlu3Ahsen Zeyrek4Mehmet Soy5Bakırköy Dr. Sadi Konuk Research and Training Hospital, Department of Rheumatology, IstanbulAbant Izzet Baysal University, Faculty of Medicine, Department of Internal MedicineAbant Izzet Baysal University, Faculty of Medicine, Department of PathologyAbant Izzet Baysal University, Faculty of Medicine, Department of Internal MedicineAbant Izzet Baysal University, Faculty of Medicine, Department of Internal MedicineHısar Intercontinental Hospial, Department of Rheumatology Hemophagocytic syndrome (HS) is a rare clinical condition characterized by fever and cytopenia due to phagocytosis of erythrocytes, leukocytes, platelets and their precursors in the bone marrow and other reticuloendothelial systems. The presence of HS can be associated with malignancies, infections, drugs and a variety of other medical disorders. We report a patient with seronegative spondyloarthropathy treated with sulfasalazine and was complicated by the occurrence of fever, facial erythema and pancytopenia. The patient was diagnosed with HS and successfully treated with corticosteroids. https://mjhid.org/index.php/mjhid/article/view/1938Hemophagocytosissulfasalazineseronegative spondyloarthropathy
collection DOAJ
language English
format Article
sources DOAJ
author Cemal Bes
Uğur Özensoy
Serdar Yanık
Pınar Memedoğlu
Ahsen Zeyrek
Mehmet Soy
spellingShingle Cemal Bes
Uğur Özensoy
Serdar Yanık
Pınar Memedoğlu
Ahsen Zeyrek
Mehmet Soy
Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
Mediterranean Journal of Hematology and Infectious Diseases
Hemophagocytosis
sulfasalazine
seronegative spondyloarthropathy
author_facet Cemal Bes
Uğur Özensoy
Serdar Yanık
Pınar Memedoğlu
Ahsen Zeyrek
Mehmet Soy
author_sort Cemal Bes
title Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
title_short Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
title_full Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
title_fullStr Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
title_full_unstemmed Hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
title_sort hemophagocytic syndrome due to sulfasalazine therapy in a patient with seronegative spondyloarthropathy
publisher PAGEPress Publications
series Mediterranean Journal of Hematology and Infectious Diseases
issn 2035-3006
publishDate 2014-08-01
description Hemophagocytic syndrome (HS) is a rare clinical condition characterized by fever and cytopenia due to phagocytosis of erythrocytes, leukocytes, platelets and their precursors in the bone marrow and other reticuloendothelial systems. The presence of HS can be associated with malignancies, infections, drugs and a variety of other medical disorders. We report a patient with seronegative spondyloarthropathy treated with sulfasalazine and was complicated by the occurrence of fever, facial erythema and pancytopenia. The patient was diagnosed with HS and successfully treated with corticosteroids.
topic Hemophagocytosis
sulfasalazine
seronegative spondyloarthropathy
url https://mjhid.org/index.php/mjhid/article/view/1938
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AT ugurozensoy hemophagocyticsyndromeduetosulfasalazinetherapyinapatientwithseronegativespondyloarthropathy
AT serdaryanık hemophagocyticsyndromeduetosulfasalazinetherapyinapatientwithseronegativespondyloarthropathy
AT pınarmemedoglu hemophagocyticsyndromeduetosulfasalazinetherapyinapatientwithseronegativespondyloarthropathy
AT ahsenzeyrek hemophagocyticsyndromeduetosulfasalazinetherapyinapatientwithseronegativespondyloarthropathy
AT mehmetsoy hemophagocyticsyndromeduetosulfasalazinetherapyinapatientwithseronegativespondyloarthropathy
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