Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies
During recent years, an increasing number of neuromuscular diseases have been recognized either to be caused primarily by autoimmune mechanisms, or to have important autoimmune components. The involved pathophysiological mechanisms and clinical manifestations have been better recognized and many of...
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Academia Brasileira de Neurologia (ABNEURO)
2014-12-01
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doaj-3a89929f561e4f839c53637ac5f7987d2020-11-24T23:25:17ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272014-12-01721296697110.1590/0004-282X20140160S0004-282X2014001200966Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathiesPaulo Victor Sgobbi de SouzaWladimir Bocca Vieira de Rezende PintoAcary Souza Bulle OliveiraDuring recent years, an increasing number of neuromuscular diseases have been recognized either to be caused primarily by autoimmune mechanisms, or to have important autoimmune components. The involved pathophysiological mechanisms and clinical manifestations have been better recognized and many of these disorders are potentially treatable by immunosuppression or by immunomodulation with intravenous immunoglobulin (IVIg). IVIg has been tried in a variety of immune-mediated neurological diseases, being target of widespread use in central and peripheral nervous systems diseases. Objective To give an overview of the main topics regarding the mechanism of action and different therapeutic uses of IVIg in neurological practice, mainly in neuromuscular diseases.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014001200966&lng=en&tlng=enimunoglobulinadoenças neuromuscularesautoimunidademiopatia inflamatória |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Paulo Victor Sgobbi de Souza Wladimir Bocca Vieira de Rezende Pinto Acary Souza Bulle Oliveira |
spellingShingle |
Paulo Victor Sgobbi de Souza Wladimir Bocca Vieira de Rezende Pinto Acary Souza Bulle Oliveira Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies Arquivos de Neuro-Psiquiatria imunoglobulina doenças neuromusculares autoimunidade miopatia inflamatória |
author_facet |
Paulo Victor Sgobbi de Souza Wladimir Bocca Vieira de Rezende Pinto Acary Souza Bulle Oliveira |
author_sort |
Paulo Victor Sgobbi de Souza |
title |
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies |
title_short |
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies |
title_full |
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies |
title_fullStr |
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies |
title_full_unstemmed |
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies |
title_sort |
clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies |
publisher |
Academia Brasileira de Neurologia (ABNEURO) |
series |
Arquivos de Neuro-Psiquiatria |
issn |
1678-4227 |
publishDate |
2014-12-01 |
description |
During recent years, an increasing number of neuromuscular diseases have been recognized either to be caused primarily by autoimmune mechanisms, or to have important autoimmune components. The involved pathophysiological mechanisms and clinical manifestations have been better recognized and many of these disorders are potentially treatable by immunosuppression or by immunomodulation with intravenous immunoglobulin (IVIg). IVIg has been tried in a variety of immune-mediated neurological diseases, being target of widespread use in central and peripheral nervous systems diseases. Objective To give an overview of the main topics regarding the mechanism of action and different therapeutic uses of IVIg in neurological practice, mainly in neuromuscular diseases. |
topic |
imunoglobulina doenças neuromusculares autoimunidade miopatia inflamatória |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014001200966&lng=en&tlng=en |
work_keys_str_mv |
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1725558328042455040 |