Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers

Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers

By employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe...

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Main Authors: Bao-Hua Song, Xing Ding, Chen Li, Gui-Feng An
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Crystals
Subjects:
coordination compounds
X-ray
cancer cells
Online Access:http://www.mdpi.com/2073-4352/8/5/207
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spelling doaj-3a8da49b2baa4349a6ab7a4bcfd0b1372020-11-24T22:18:44ZengMDPI AGCrystals2073-43522018-05-018520710.3390/cryst8050207cryst8050207Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination PolymersBao-Hua Song0Xing Ding1Chen Li2Gui-Feng An3Medical College, Inner Mongolia University for Nationalities, Tongliao 028000, ChinaDepartment of Neurosurgery, Shaoxing Second Hospital, Shaoxing 312000, ChinaMedical College, Inner Mongolia University for Nationalities, Tongliao 028000, ChinaMedical College, Inner Mongolia University for Nationalities, Tongliao 028000, ChinaBy employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe(CN)3]2[M(Bim)2](H2O)2}n [M = Cu(II) for 2 and Mn(II) for 3, Bim = bis(1-imidazolyl)methane] were synthesized by making use of different nitrogen-containing organic linkers. Furthermore, in vitro cytotoxicity of compounds 1–3 was studied against four human liver cancer cells (HepG2, Bel-7402, SMMC7721, and MHCC97) via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay experiments.http://www.mdpi.com/2073-4352/8/5/207coordination compoundsX-raycancer cells
collection DOAJ
language English
format Article
sources DOAJ
author Bao-Hua Song
Xing Ding
Chen Li
Gui-Feng An
spellingShingle Bao-Hua Song
Xing Ding
Chen Li
Gui-Feng An
Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
Crystals
coordination compounds
X-ray
cancer cells
author_facet Bao-Hua Song
Xing Ding
Chen Li
Gui-Feng An
author_sort Bao-Hua Song
title Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
title_short Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
title_full Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
title_fullStr Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
title_full_unstemmed Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
title_sort synthesis, crystal structures, and anti-liver cancer activity studies on three similar coordination polymers
publisher MDPI AG
series Crystals
issn 2073-4352
publishDate 2018-05-01
description By employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe(CN)3]2[M(Bim)2](H2O)2}n [M = Cu(II) for 2 and Mn(II) for 3, Bim = bis(1-imidazolyl)methane] were synthesized by making use of different nitrogen-containing organic linkers. Furthermore, in vitro cytotoxicity of compounds 1–3 was studied against four human liver cancer cells (HepG2, Bel-7402, SMMC7721, and MHCC97) via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay experiments.
topic coordination compounds
X-ray
cancer cells
url http://www.mdpi.com/2073-4352/8/5/207
work_keys_str_mv AT baohuasong synthesiscrystalstructuresandantilivercanceractivitystudiesonthreesimilarcoordinationpolymers
AT xingding synthesiscrystalstructuresandantilivercanceractivitystudiesonthreesimilarcoordinationpolymers
AT chenli synthesiscrystalstructuresandantilivercanceractivitystudiesonthreesimilarcoordinationpolymers
AT guifengan synthesiscrystalstructuresandantilivercanceractivitystudiesonthreesimilarcoordinationpolymers
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