Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers
By employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe...
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doaj-3a8da49b2baa4349a6ab7a4bcfd0b1372020-11-24T22:18:44ZengMDPI AGCrystals2073-43522018-05-018520710.3390/cryst8050207cryst8050207Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination PolymersBao-Hua Song0Xing Ding1Chen Li2Gui-Feng An3Medical College, Inner Mongolia University for Nationalities, Tongliao 028000, ChinaDepartment of Neurosurgery, Shaoxing Second Hospital, Shaoxing 312000, ChinaMedical College, Inner Mongolia University for Nationalities, Tongliao 028000, ChinaMedical College, Inner Mongolia University for Nationalities, Tongliao 028000, ChinaBy employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe(CN)3]2[M(Bim)2](H2O)2}n [M = Cu(II) for 2 and Mn(II) for 3, Bim = bis(1-imidazolyl)methane] were synthesized by making use of different nitrogen-containing organic linkers. Furthermore, in vitro cytotoxicity of compounds 1–3 was studied against four human liver cancer cells (HepG2, Bel-7402, SMMC7721, and MHCC97) via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay experiments.http://www.mdpi.com/2073-4352/8/5/207coordination compoundsX-raycancer cells |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bao-Hua Song Xing Ding Chen Li Gui-Feng An |
spellingShingle |
Bao-Hua Song Xing Ding Chen Li Gui-Feng An Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers Crystals coordination compounds X-ray cancer cells |
author_facet |
Bao-Hua Song Xing Ding Chen Li Gui-Feng An |
author_sort |
Bao-Hua Song |
title |
Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers |
title_short |
Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers |
title_full |
Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers |
title_fullStr |
Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers |
title_full_unstemmed |
Synthesis, Crystal Structures, and Anti-Liver Cancer Activity Studies on Three Similar Coordination Polymers |
title_sort |
synthesis, crystal structures, and anti-liver cancer activity studies on three similar coordination polymers |
publisher |
MDPI AG |
series |
Crystals |
issn |
2073-4352 |
publishDate |
2018-05-01 |
description |
By employment of a pre-designed molecular building block [(pzTp)Fe(CN)3], one cyano-bridged trinuclear complex [MnMe4TACD][(pzTp)Fe(CN)3]2(H2O)16 1, [pzTp = tetrakis(pyrazoly)borate, Me4TACD = 1,4,7,10-tetramethyl-1,4,7,10-tetraazacyclododecane] and two 1D chain-like coordination polymers {[(pzTp)Fe(CN)3]2[M(Bim)2](H2O)2}n [M = Cu(II) for 2 and Mn(II) for 3, Bim = bis(1-imidazolyl)methane] were synthesized by making use of different nitrogen-containing organic linkers. Furthermore, in vitro cytotoxicity of compounds 1–3 was studied against four human liver cancer cells (HepG2, Bel-7402, SMMC7721, and MHCC97) via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay experiments. |
topic |
coordination compounds X-ray cancer cells |
url |
http://www.mdpi.com/2073-4352/8/5/207 |
work_keys_str_mv |
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