Increased Phosphaturia Accelerates The Decline in Renal Function: A Search for Mechanisms
Abstract In chronic kidney disease (CKD), high serum phosphate concentration is associated with cardiovascular disease and deterioration in renal function. In early CKD, the serum phosphate concentration is normal due to increased fractional excretion of phosphate. Our premise was that high phosphat...
Main Authors: | Rafael Santamaría, Juan M. Díaz-Tocados, M. Victoria Pendón-Ruiz de Mier, Ana Robles, M. Dolores Salmerón-Rodríguez, Erena Ruiz, Noemi Vergara, Escolástico Aguilera-Tejero, Ana Raya, Rosa Ortega, Arnold Felsenfeld, Juan R. Muñoz-Castañeda, Alejandro Martín-Malo, Pedro Aljama, Mariano Rodríguez |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-09-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-018-32065-2 |
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