The Role of Sirt1 in Ischemic Stroke: Pathogenesis and Therapeutic Strategies

The Role of Sirt1 in Ischemic Stroke: Pathogenesis and Therapeutic Strategies

Silent mating type information regulation 2 homolog 1 (Sirt1), a nicotine adenine dinucleotide (NAD+)-dependent enzyme, is well-known in playing a part in longevity. Ischemic stroke is a major neurological disorder and is a leading cause of death and adult disability worldwide. Recently, many studie...

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Bibliographic Details
Main Authors: Jun-Fang Zhang, Yu-Lei Zhang, Yun-Cheng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neuroscience
Subjects:
Sirt1
deacetylase
ischemic stroke
neuroprotection
sirtuin
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00833/full

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