Evaluation and Prediction of the HIV-1 Central Polypurine Tract Influence on Foamy Viral Vectors to Transduce Dividing and Growth-Arrested Cells

Evaluation and Prediction of the HIV-1 Central Polypurine Tract Influence on Foamy Viral Vectors to Transduce Dividing and Growth-Arrested Cells

Retroviral vectors are potent tools for gene delivery and various biomedical applications. To accomplish a gene transfer task successfully, retroviral vectors must effectively transduce diverse cell cultures at different phases of a cell cycle. However, very promising retroviral vectors based on the...

Full description

Bibliographic Details
Main Authors:	Sergey Shityakov, Carola Förster, Axel Rethwilm, Thomas Dandekar
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/487969

Similar Items

Foamy Virus Biology and Its Application for Vector Development
by: Axel Rethwilm, et al.
Published: (2011-05-01)

SiRNA-induced mutation in HIV-1 polypurine tract region and its influence on viral fitness.
by: Jason W Rausch, et al.
Published: (2015-01-01)

Regulation of foamy virus protease activity by viral RNA
by: Hartl Maximilian J, et al.
Published: (2011-06-01)

Prospects for Foamy Viral Vector Anti-HIV Gene Therapy
by: Arun K. Nalla, et al.
Published: (2016-03-01)

Evolution of Foamy Viruses: The Most Ancient of All Retroviruses
by: Jochen Bodem, et al.
Published: (2013-09-01)

Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice
by: John R. Counsell, et al.
Published: (2018-09-01)

Viral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract.
by: Gauri R Nair, et al.
Published: (2012-01-01)

Foamy Virus Vectors for HIV Gene Therapy
by: Grant D. Trobridge, et al.
Published: (2013-10-01)

Novel strategies for HIV-1 epitope delivery using foamy viral hybrid proteins and vectors
by: Mühle M, et al.
Published: (2012-09-01)

How Polypurine Tract Changes in the HIV-1 RNA Genome Can Cause Resistance against the Integrase Inhibitor Dolutegravir
by: Atze T. Das, et al.
Published: (2018-04-01)

Accuracy estimation of foamy virus genome copying
by: Rethwilm Axel, et al.
Published: (2009-04-01)

Variability in HIV-1 Integrase Gene and 3′-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy
by: Arpan Acharya, et al.
Published: (2020-02-01)

Determination of the relative amounts of Gag and Pol proteins in foamy virus particles
by: Herchenröder Ottmar, et al.
Published: (2005-07-01)

Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases
by: Wöhrl Birgitta M, et al.
Published: (2010-01-01)

The prototype foamy virus protease is active independently of the integrase domain
by: Spannaus Ralf, et al.
Published: (2012-05-01)

Viral caracterisation of “zoonotic” Foamy viruses
by: Gessain Antoine, et al.
Published: (2011-06-01)

Reply to Das and Berkhout, “How Polypurine Tract Changes in the HIV-1 RNA Genome Can Cause Resistance against the Integrase Inhibitor Dolutegravir”
by: Isabelle Malet, et al.
Published: (2018-05-01)

Modeling of shotgun sequencing of DNA plasmids using experimental and theoretical approaches
by: Sergey Shityakov, et al.
Published: (2020-04-01)

Structural and Functional Insights into Foamy Viral Integrase
by: Cha-Gyun Shin, et al.
Published: (2013-07-01)

Production and application of foamy virus-derived vectors
by: Patton, Gillian Sarah
Published: (2006)

A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance
by: Elizabeth M Everson, et al.
Published: (2016-01-01)

An endogenous foamy-like viral element in the coelacanth genome.
by: Guan-Zhu Han, et al.
Published: (2012-01-01)

Pharmacokinetic Delivery and Metabolizing Rate of Nicardipine Incorporated in Hydrophilic and Hydrophobic Cyclodextrins Using Two-Compartment Mathematical Model
by: Sergey Shityakov, et al.
Published: (2013-01-01)

Delivery of large transgene cassettes by foamy virus vector
by: Nathan Paul Sweeney, et al.
Published: (2017-08-01)

Foamy virus vector integration and application in gene therapy
by: Sweeney, Nathan Paul
Published: (2015)

PolyPurine Reverse Hoogsteen Hairpins Work as RNA Species for Gene Silencing
by: Eva Aubets, et al.
Published: (2021-09-01)

Large Animal Models for Foamy Virus Vector Gene Therapy
by: Peter A. Horn, et al.
Published: (2012-12-01)

Prototype foamy virus gene expression and hybrid vector development
by: Russell, Rebecca Alice
Published: (2003)

The development of prototypic foamy virus as a gene therapy vector
by: Menon, Dev Christophe
Published: (2009)

Rational Drug Design of Axl Tyrosine Kinase Type I Inhibitors as Promising Candidates Against Cancer
by: Edita Sarukhanyan, et al.
Published: (2020-02-01)

Palmitoylation of the Bovine Foamy Virus Envelope Glycoprotein Is Required for Viral Replication
by: Keli Chai, et al.
Published: (2021-12-01)

Viral latency in blood and saliva of simian foamy virus-infected humans.
by: Rejane Rua, et al.
Published: (2013-01-01)

Feline Foamy Virus-Based Vectors: Advantages of an Authentic Animal Model
by: Martin Löchelt, et al.
Published: (2013-07-01)

Polypurine Reverse-Hoogsteen Hairpins as a Tool for Exon Skipping at the Genomic Level in Mammalian Cells
by: Véronique Noé, et al.
Published: (2021-04-01)

Cellular Effects of Replicating a Polypurine-Polypyrimidine Sequence and the Interactions of DUE-B with Replication Proteins
by: Myers, Shere Lynne
Published: (2010)

In silico predictive model to determine vector-mediated transport properties for the blood–brain barrier choline transporter
by: Shityakov S, et al.
Published: (2014-09-01)

Prototype foamy virus downregulates RelB expression to facilitate viral replication
by: Junshi Zhang, et al.
Published: (2020-10-01)

Isolation of an Equine Foamy Virus and Sero-Epidemiology of the Viral Infection in Horses in Japan
by: Rikio Kirisawa, et al.
Published: (2019-07-01)

Replication-Competent Foamy Virus Vaccine Vectors as Novel Epitope Scaffolds for Immunotherapy.
by: Janet Lei, et al.
Published: (2015-01-01)

Orthoretroviral-like prototype foamy virus gag-pol expression is compatible with viral replication
by: Reh Juliane, et al.
Published: (2011-08-01)