Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation
OBJECTIVES/BACKGROUND:. Extracorporeal membrane oxygenation is used as rescue therapy for patients with acute respiratory distress syndrome in whom conventional therapy has failed prior to an Extra Corporeal Membrane Oxygenator to rescue Lung Injury in Severe Acute Respiratory Distress Syndrome tria...
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2021-06-01
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doaj-3aad5ec3aa4642b0a3b69b7899fb07962021-06-28T03:11:59ZengWolters KluwerCritical Care Explorations2639-80282021-06-0136e045410.1097/CCE.0000000000000454202106000-00002Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical VentilationMohamed H. Azzam, MD, FRCPC, FCCM0Hani N. Mufti, MD MHI, CIP, FRCSC1Husam Bahaudden, MD, FRCPC2Ahmed Z. Ragab, MD3Mahdi M. Othman, MD4Wail A. Tashkandi, MD, ABS, FCCM51 Department of Intensive Care, King Abdullah Medical Complex, Ministry of Health, Jeddah, Saudi Arabia.2 Department of Cardiac Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia.3 Department Cardiac Sciences, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia.6 Department of Intensive Care, King Fahad General Hospital, Ministry of Health, Jeddah, Saudi Arabia.1 Department of Intensive Care, King Abdullah Medical Complex, Ministry of Health, Jeddah, Saudi Arabia.7 Department of Adult Intensive Care Unit, Fakeeh Care Group, Jeddah, Saudi Arabia.OBJECTIVES/BACKGROUND:. Extracorporeal membrane oxygenation is used as rescue therapy for patients with acute respiratory distress syndrome in whom conventional therapy has failed prior to an Extra Corporeal Membrane Oxygenator to rescue Lung Injury in Severe Acute Respiratory Distress Syndrome trial. Since then, extracorporeal membrane oxygenation has been incorporated as part of the standard treatment algorithm in many centers for patients with severe acute respiratory distress syndrome. Since the emergence of coronavirus disease 2019 in early 2020, extracorporeal membrane oxygenation has been used effectively as rescue therapy and as a bridge to recovery in some patients with refractory respiratory failure. DESIGN, SUBJECT, AND INTERVENTION:. We present a 38-year-old male healthcare worker diagnosed with coronavirus disease 2019 and progressed to critical condition with severe surgical emphysema on a high-flow nasal cannula with Fio2 100%, a flow of 40 L/min, and a maximum oxygen saturation of 88%. He was successfully treated by applying awake extracorporeal membrane oxygenation, without a need for invasive mechanical ventilation, to avoid worsening barotrauma and hemodynamic compromise potentially induced by positive pressure ventilation. MAIN RESULTS AND CONCLUSIONS:. To our knowledge, this is one of the first cases to be reported in the literature on the use of awake extracorporeal membrane oxygenation as a “treatment” for barotrauma due to severe acute respiratory distress syndrome in a coronavirus disease 2019 patient, without the need for invasive mechanical ventilation. In selected patients with severe respiratory failure, awake extracorporeal membrane oxygenation can be used as a salvage treatment and obviate the need for invasive mechanical ventilation.http://journals.lww.com/10.1097/CCE.0000000000000454 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohamed H. Azzam, MD, FRCPC, FCCM Hani N. Mufti, MD MHI, CIP, FRCSC Husam Bahaudden, MD, FRCPC Ahmed Z. Ragab, MD Mahdi M. Othman, MD Wail A. Tashkandi, MD, ABS, FCCM |
spellingShingle |
Mohamed H. Azzam, MD, FRCPC, FCCM Hani N. Mufti, MD MHI, CIP, FRCSC Husam Bahaudden, MD, FRCPC Ahmed Z. Ragab, MD Mahdi M. Othman, MD Wail A. Tashkandi, MD, ABS, FCCM Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation Critical Care Explorations |
author_facet |
Mohamed H. Azzam, MD, FRCPC, FCCM Hani N. Mufti, MD MHI, CIP, FRCSC Husam Bahaudden, MD, FRCPC Ahmed Z. Ragab, MD Mahdi M. Othman, MD Wail A. Tashkandi, MD, ABS, FCCM |
author_sort |
Mohamed H. Azzam, MD, FRCPC, FCCM |
title |
Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation |
title_short |
Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation |
title_full |
Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation |
title_fullStr |
Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation |
title_full_unstemmed |
Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation |
title_sort |
awake extracorporeal membrane oxygenation in coronavirus disease 2019 patients without invasive mechanical ventilation |
publisher |
Wolters Kluwer |
series |
Critical Care Explorations |
issn |
2639-8028 |
publishDate |
2021-06-01 |
description |
OBJECTIVES/BACKGROUND:. Extracorporeal membrane oxygenation is used as rescue therapy for patients with acute respiratory distress syndrome in whom conventional therapy has failed prior to an Extra Corporeal Membrane Oxygenator to rescue Lung Injury in Severe Acute Respiratory Distress Syndrome trial. Since then, extracorporeal membrane oxygenation has been incorporated as part of the standard treatment algorithm in many centers for patients with severe acute respiratory distress syndrome. Since the emergence of coronavirus disease 2019 in early 2020, extracorporeal membrane oxygenation has been used effectively as rescue therapy and as a bridge to recovery in some patients with refractory respiratory failure.
DESIGN, SUBJECT, AND INTERVENTION:. We present a 38-year-old male healthcare worker diagnosed with coronavirus disease 2019 and progressed to critical condition with severe surgical emphysema on a high-flow nasal cannula with Fio2 100%, a flow of 40 L/min, and a maximum oxygen saturation of 88%. He was successfully treated by applying awake extracorporeal membrane oxygenation, without a need for invasive mechanical ventilation, to avoid worsening barotrauma and hemodynamic compromise potentially induced by positive pressure ventilation.
MAIN RESULTS AND CONCLUSIONS:. To our knowledge, this is one of the first cases to be reported in the literature on the use of awake extracorporeal membrane oxygenation as a “treatment” for barotrauma due to severe acute respiratory distress syndrome in a coronavirus disease 2019 patient, without the need for invasive mechanical ventilation. In selected patients with severe respiratory failure, awake extracorporeal membrane oxygenation can be used as a salvage treatment and obviate the need for invasive mechanical ventilation. |
url |
http://journals.lww.com/10.1097/CCE.0000000000000454 |
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