Preclinical studies of toxicity and safety of the AS-48 bacteriocin

Preclinical studies of toxicity and safety of the AS-48 bacteriocin

The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice...

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Main Authors: Rubén Cebrián, M. Elena Rodríguez-Cabezas, Rubén Martín-Escolano, Susana Rubiño, María Garrido-Barros, Manuel Montalbán-López, María José Rosales, Manuel Sánchez-Moreno, Eva Valdivia, Manuel Martínez-Bueno, Clotilde Marín, Julio Gálvez, Mercedes Maqueda
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Advanced Research
Online Access:http://www.sciencedirect.com/science/article/pii/S209012321930133X

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