Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2)

<p>Abstract</p> <p>Background</p> <p>Pituitary tumor transforming gene (PTTG) is a novel oncogene that is expressed at higher level in most of the tumors analyzed to date compared to normal tissues. Existence of a relationship between PTTG levels and tumor angiogenesis...

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Bibliographic Details
Main Authors: Kakar Sham S, Malik Mohammad T
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/61