Inhibitory Synapse Formation at the Axon Initial Segment

Inhibitory Synapse Formation at the Axon Initial Segment

The axon initial segment (AIS) is the site of action potential (AP) initiation in most neurons and is thus a critical site in the regulation of neuronal excitability. Normal function within the discrete AIS compartment requires intricate molecular machinery to ensure the proper concentration and org...

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Bibliographic Details
Main Authors: Anna J. Nathanson, Paul A. Davies, Stephen J. Moss
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
GABAA receptor
axon initial segment
collybistin
gephyrin
inhibition
synapse formation
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00266/full

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