Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus

Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus

Conjugative transfer is a major threat to global health since it contributes to the spread of antibiotic resistance genes and virulence factors among commensal and pathogenic bacteria. To allow their transfer, mobile genetic elements including Integrative and Conjugative Elements (ICEs) use a specia...

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Bibliographic Details
Main Authors:	Julien Cappele, Abbas Mohamad Ali, Nathalie Leblond-Bourget, Sandrine Mathiot, Tiphaine Dhalleine, Sophie Payot, Martin Savko, Claude Didierjean, Frédérique Favier, Badreddine Douzi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-03-01
Series:	Frontiers in Molecular Biosciences
Subjects:	conjugation Gram - positive bacteria type IV secretion system Integrative and Conjugative Element (ICE) VirB8-like proteins
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2021.642606/full

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