Human cardiomyocytes for drug discovery

Human cardiomyocytes for drug discovery

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Introduction: Cardiac drug discovery are based in old methods that use animals, animal cells or modified cells that do not faithfully represent human cardiac phenotypes. Objective: Here, we aimed to show that cardiomyocytes derived from human iPS cells represent a new tool for cardiac drug discovery...

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Main Authors: Diogo Gonçalves Biagi, Jéssica Gonçalves, Estela Cruvinel, Renata Damiani, Flavia Valgode, Fabiana Medeiros, Camila G Moreira, Evelyn Santos, Rodrigo Marcon, Calixto João, Gabriela Venturini, Alexandre Pereira, Éden Ferreira, Renato Mortara, Marcos C Valadares
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2018-02-01
Series:Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia
Subjects:
Human Cardiomyocytes
Drug Discovery
Doxorubicin
Animal Replacement
Online Access:https://hm-visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1049

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