PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMP

PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMP

Skin circadian clock system responds to daily changes, thereby regulating skin functions. Exposure of the skin to UV irradiation induces the expression of matrix metalloproteinase-1 (MMP-1) and causes DNA damage. It has been reported both DNA repair and DNA replication are regulated by the circadian...

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Bibliographic Details
Main Authors: Miji Yeom, HansongI Lee, Seoungwoo Shin, Deokhoon Park, Eunsun Jung
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
skin circadian clock
PER
MMP-1
cAMP
Lespedeza capitata
Online Access:http://www.mdpi.com/1420-3049/23/4/745

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