Oxidative stress in mammalian cells impinges on the cysteines redox state of human XRCC3 protein and on its cellular localization.
In vertebrates, XRCC3 is one of the five Rad51 paralogs that plays a central role in homologous recombination (HR), a key pathway for maintaining genomic stability. While investigating the potential role of human XRCC3 (hXRCC3) in the inhibition of DNA replication induced by UVA radiation, we discov...
Main Authors: | Pierre-Marie Girard, Dany Graindorge, Violetta Smirnova, Pascal Rigolet, Stefania Francesconi, Susan Scanlon, Evelyne Sage |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3793007?pdf=render |
Similar Items
-
Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication.
by: Dany Graindorge, et al.
Published: (2015-01-01) -
Association of XRCC1, XRCC2 and XRCC3 Gene Polymorphism with Esophageal Cancer Risk
by: Kaur J, et al.
Published: (2020-03-01) -
Association Studies Between XRCC1, XRCC2, XRCC3 Polymorphisms and Differentiated Thyroid Carcinoma
by: Li Yan, et al.
Published: (2016-03-01) -
Cysteine, Glutathione, and Thiol Redox Balance in Astrocytes
by: Gethin J. McBean
Published: (2017-08-01) -
Cysteine-based redox regulation and signalling in plants
by: Jérémy eCouturier, et al.
Published: (2013-04-01)