Validation of loop-mediated isothermal amplification for the detection of Loa loa infection in Chrysops spp in experimental and natural field conditions

Validation of loop-mediated isothermal amplification for the detection of Loa loa infection in Chrysops spp in experimental and natural field conditions

Abstract Background The mass drug administration of ivermectin for onchocerciasis control has contributed to a significant drop in Loa loa microfilaria loads in humans that has, in turn, led to reduction of infection levels in Chrysops vectors. Accurate parasite detection is essential for assessing...

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Bibliographic Details
Main Authors: Glory Ngongeh Amambo, Raphael Awah Abong, Fanny Fri Fombad, Abdel Jelil Njouendou, Franck Nietcho, Amuam Andrew Beng, Ritter Manuel, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Peter Ivo Enyong, Catherine Poole, Achim Hoerauf, Clotilde Carlow, Samuel Wanji
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Parasites & Vectors
Subjects:
Loa loa
Chrysops
RF4-based LAMP
Microscopy
Ivermectin
Online Access:https://doi.org/10.1186/s13071-020-04506-3

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