Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases

Age-related macular degeneration(ARMD)and Stargardt's macular dystrophy(SMD)are two kinds of degenerative retinal diseases that respectively lead to irreversible vision loss of the elderly and juvenile population. However, the severe visual impairment in dry ARMD and SMD remains untreatable. In...

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Bibliographic Details
Main Authors: Tian-Yue Cao, Shuang-Hong Jiang, Chen Yan, Ming Ai
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-12-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2017/12/201712017.pdf
Description
Summary:Age-related macular degeneration(ARMD)and Stargardt's macular dystrophy(SMD)are two kinds of degenerative retinal diseases that respectively lead to irreversible vision loss of the elderly and juvenile population. However, the severe visual impairment in dry ARMD and SMD remains untreatable. In recent years, with the advancement of stem cell technology, stem cell-derived RPE cell transplantation therapy of retinal degeneration has become new research hotspot and direction. This article reviewed the progress of stem cell based approaches for treating retinal degenerative diseases and discussed the prospect and challenges in this field.
ISSN:1672-5123
1672-5123