Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases
Age-related macular degeneration(ARMD)and Stargardt's macular dystrophy(SMD)are two kinds of degenerative retinal diseases that respectively lead to irreversible vision loss of the elderly and juvenile population. However, the severe visual impairment in dry ARMD and SMD remains untreatable. In...
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Press of International Journal of Ophthalmology (IJO PRESS)
2017-12-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2017/12/201712017.pdf |
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doaj-3b27f1121bf848e5a7f56c7a61b539b22020-11-24T21:58:14ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232017-12-0117122260226210.3980/j.issn.1672-5123.2017.12.17Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseasesTian-Yue Cao0Shuang-Hong Jiang1Chen Yan2Ming Ai3Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaAge-related macular degeneration(ARMD)and Stargardt's macular dystrophy(SMD)are two kinds of degenerative retinal diseases that respectively lead to irreversible vision loss of the elderly and juvenile population. However, the severe visual impairment in dry ARMD and SMD remains untreatable. In recent years, with the advancement of stem cell technology, stem cell-derived RPE cell transplantation therapy of retinal degeneration has become new research hotspot and direction. This article reviewed the progress of stem cell based approaches for treating retinal degenerative diseases and discussed the prospect and challenges in this field.http://ies.ijo.cn/cn_publish/2017/12/201712017.pdfdegenerative retinal dieasesage-related macular degenerationstem cell-based therapyretinal pigment epitheliumretinal pigment epithelium |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Tian-Yue Cao Shuang-Hong Jiang Chen Yan Ming Ai |
| spellingShingle |
Tian-Yue Cao Shuang-Hong Jiang Chen Yan Ming Ai Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases Guoji Yanke Zazhi degenerative retinal dieases age-related macular degeneration stem cell-based therapy retinal pigment epithelium retinal pigment epithelium |
| author_facet |
Tian-Yue Cao Shuang-Hong Jiang Chen Yan Ming Ai |
| author_sort |
Tian-Yue Cao |
| title |
Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases |
| title_short |
Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases |
| title_full |
Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases |
| title_fullStr |
Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases |
| title_full_unstemmed |
Research progress of stem cell-derived RPE cell transplantation therapy for retinal degenerative diseases |
| title_sort |
research progress of stem cell-derived rpe cell transplantation therapy for retinal degenerative diseases |
| publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
| series |
Guoji Yanke Zazhi |
| issn |
1672-5123 1672-5123 |
| publishDate |
2017-12-01 |
| description |
Age-related macular degeneration(ARMD)and Stargardt's macular dystrophy(SMD)are two kinds of degenerative retinal diseases that respectively lead to irreversible vision loss of the elderly and juvenile population. However, the severe visual impairment in dry ARMD and SMD remains untreatable. In recent years, with the advancement of stem cell technology, stem cell-derived RPE cell transplantation therapy of retinal degeneration has become new research hotspot and direction. This article reviewed the progress of stem cell based approaches for treating retinal degenerative diseases and discussed the prospect and challenges in this field. |
| topic |
degenerative retinal dieases age-related macular degeneration stem cell-based therapy retinal pigment epithelium retinal pigment epithelium |
| url |
http://ies.ijo.cn/cn_publish/2017/12/201712017.pdf |
| work_keys_str_mv |
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