Natural Killer Cell Lymphoma: A Case with Classification Dilemma
Non-Hodgkins lymphoma of the Natural Killer (NK) cell type is rare. World Health Organisation recognises 3 NK-cell phenotypic entities; extranodal NK/T cell lymphoma, nasal type (ENK/TL); aggressive NK cell leukaemia (ANKL); and chronic lymphoproliferative disorders of NK cells (CLPD-NK) which is...
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doaj-3b353e9352c04cccb87a46d7717f25bd2020-11-25T03:15:07ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-02-01102ED07ED0810.7860/JCDR/2016/15501.7177Natural Killer Cell Lymphoma: A Case with Classification DilemmaAnkit Kumar Jitani0 Yookarin Khonglah1Ritesh Kumar2Bidyut Bikash Gogoi3Ekta Jajodia4Senior Resident, Department of Pathology, NEIGRIHMS, Shillong, Meghalaya, India.Associate Professor, Department of Pathology, NEIGRIHMS, Shillong, Meghalaya, India.Assistant Professor, Department of Oncology, NEIGRIHMS, Shillong, Meghalaya, India.Junior Resident, Department of Pathology, NEIGRIHMS, Shillong, Meghalaya, India.Junior Resident, Department of Pathology, NEIGRIHMS, Shillong, Meghalaya, India.Non-Hodgkins lymphoma of the Natural Killer (NK) cell type is rare. World Health Organisation recognises 3 NK-cell phenotypic entities; extranodal NK/T cell lymphoma, nasal type (ENK/TL); aggressive NK cell leukaemia (ANKL); and chronic lymphoproliferative disorders of NK cells (CLPD-NK) which is classified as a provisional entity. Though specific clinical, morphological and immunophenotypic criteria have been laid down to diagnose these conditions there may however, be considerable variations in the clinical presentation making diagnosis difficult. We present a case with contrasting clinical and haematopathological findings posing difficulty in its diagnosis and classification, and despite the aggressive presentation showing favourable response to treatment. https://jcdr.net/articles/PDF/7177/15501_CE[Ra]_F(P)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdfflow cytometrynk-cellnon-hodgkins lymphoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ankit Kumar Jitani Yookarin Khonglah Ritesh Kumar Bidyut Bikash Gogoi Ekta Jajodia |
spellingShingle |
Ankit Kumar Jitani Yookarin Khonglah Ritesh Kumar Bidyut Bikash Gogoi Ekta Jajodia Natural Killer Cell Lymphoma: A Case with Classification Dilemma Journal of Clinical and Diagnostic Research flow cytometry nk-cell non-hodgkins lymphoma |
author_facet |
Ankit Kumar Jitani Yookarin Khonglah Ritesh Kumar Bidyut Bikash Gogoi Ekta Jajodia |
author_sort |
Ankit Kumar Jitani |
title |
Natural Killer Cell Lymphoma: A Case with Classification Dilemma |
title_short |
Natural Killer Cell Lymphoma: A Case with Classification Dilemma |
title_full |
Natural Killer Cell Lymphoma: A Case with Classification Dilemma |
title_fullStr |
Natural Killer Cell Lymphoma: A Case with Classification Dilemma |
title_full_unstemmed |
Natural Killer Cell Lymphoma: A Case with Classification Dilemma |
title_sort |
natural killer cell lymphoma: a case with classification dilemma |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2016-02-01 |
description |
Non-Hodgkins lymphoma of the Natural Killer (NK) cell type is rare. World Health Organisation recognises 3 NK-cell phenotypic entities;
extranodal NK/T cell lymphoma, nasal type (ENK/TL); aggressive NK cell leukaemia (ANKL); and chronic lymphoproliferative disorders
of NK cells (CLPD-NK) which is classified as a provisional entity. Though specific clinical, morphological and immunophenotypic criteria
have been laid down to diagnose these conditions there may however, be considerable variations in the clinical presentation making
diagnosis difficult. We present a case with contrasting clinical and haematopathological findings posing difficulty in its diagnosis and
classification, and despite the aggressive presentation showing favourable response to treatment. |
topic |
flow cytometry nk-cell non-hodgkins lymphoma |
url |
https://jcdr.net/articles/PDF/7177/15501_CE[Ra]_F(P)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdf |
work_keys_str_mv |
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1724640468315144192 |