Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting

Context: We studied the relationship between intraoperative transesophageal echocardiography-derived (TEE-derived) pulmonary artery systolic pressure (PASP) measurements with early morbidity in on-pump coronary artery bypass grafting (CABG) surgery. Aims: The objective of the study was to assess whe...

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Main Authors: Hariharan Subramanian, Satyen Parida, Chitra Rajeswari Thangaswamy, Ashok Shankar Badhe, B V Sai Chandran, Sandeep Kumar Mishra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Annals of Cardiac Anaesthesia
Subjects:
Online Access:http://www.annals.in/article.asp?issn=0971-9784;year=2020;volume=23;issue=4;spage=453;epage=459;aulast=Subramanian
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spelling doaj-3b38067503804ac39ff190fbac8e56602020-11-25T04:06:54ZengWolters Kluwer Medknow PublicationsAnnals of Cardiac Anaesthesia0971-97842020-01-0123445345910.4103/aca.ACA_161_19Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass graftingHariharan SubramanianSatyen ParidaChitra Rajeswari ThangaswamyAshok Shankar BadheB V Sai ChandranSandeep Kumar MishraContext: We studied the relationship between intraoperative transesophageal echocardiography-derived (TEE-derived) pulmonary artery systolic pressure (PASP) measurements with early morbidity in on-pump coronary artery bypass grafting (CABG) surgery. Aims: The objective of the study was to assess whether TEE-derived elevated PASP is independently predictive of significant morbidity. Settings and Design: Prospective observational study in a university hospital. Materials and Methods: Around 54 patients who underwent CABG under cardiopulmonary bypass (CPB) were divided into two groups; with PASP ≥35 mmHg and PASP <35 mmHg, assessed by intraoperative TEE. Outcomes studied were poor coronary revascularization, postoperative arrhythmias, myocardial infarction, respiratory failure, intra-aortic balloon pump use, pacemaker dependence, significant inotrope use, prolonged intensive care unit stay, and the total length of stay in the hospital. Mortality analysis was not a part of this study since expected sample sizes were low. Results: Patients with PASP ≥35 mmHg had a higher risk of respiratory failure, increased inotrope use and prolonged hospital stay, although multivariate analysis failed to demonstrate an independent association of PASP with these outcomes. Diabetes mellitus (DM), peripheral vascular disease, low cardiac output and elevated mitral annular E/e' ratio were significantly associated with higher pulmonary arterial pressures. Multivariate analysis showed that PASP was independently associated with higher mitral annular E/e' ratio. Conclusions: Our study, therefore, suggests that higher PASP may predict higher left ventricular filling pressures, and although elevated PASP ≥35 mmHg may be associated with DM; peripheral vascular disease, lower intraoperative cardiac output, postoperative respiratory failure, higher inotrope use, and delayed hospital discharge, it is not an independent predictor of any of these variables.http://www.annals.in/article.asp?issn=0971-9784;year=2020;volume=23;issue=4;spage=453;epage=459;aulast=Subramaniancardiopulmonary bypasscoronary artery bypass graftpulmonarysystolic pressuretransesophageal echocardiography
collection DOAJ
language English
format Article
sources DOAJ
author Hariharan Subramanian
Satyen Parida
Chitra Rajeswari Thangaswamy
Ashok Shankar Badhe
B V Sai Chandran
Sandeep Kumar Mishra
spellingShingle Hariharan Subramanian
Satyen Parida
Chitra Rajeswari Thangaswamy
Ashok Shankar Badhe
B V Sai Chandran
Sandeep Kumar Mishra
Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
Annals of Cardiac Anaesthesia
cardiopulmonary bypass
coronary artery bypass graft
pulmonary
systolic pressure
transesophageal echocardiography
author_facet Hariharan Subramanian
Satyen Parida
Chitra Rajeswari Thangaswamy
Ashok Shankar Badhe
B V Sai Chandran
Sandeep Kumar Mishra
author_sort Hariharan Subramanian
title Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
title_short Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
title_full Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
title_fullStr Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
title_full_unstemmed Relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
title_sort relationship between transesophageal echocardiography-derived pulmonary artery systolic pressure measurements and early morbidity in patients undergoing coronary artery bypass grafting
publisher Wolters Kluwer Medknow Publications
series Annals of Cardiac Anaesthesia
issn 0971-9784
publishDate 2020-01-01
description Context: We studied the relationship between intraoperative transesophageal echocardiography-derived (TEE-derived) pulmonary artery systolic pressure (PASP) measurements with early morbidity in on-pump coronary artery bypass grafting (CABG) surgery. Aims: The objective of the study was to assess whether TEE-derived elevated PASP is independently predictive of significant morbidity. Settings and Design: Prospective observational study in a university hospital. Materials and Methods: Around 54 patients who underwent CABG under cardiopulmonary bypass (CPB) were divided into two groups; with PASP ≥35 mmHg and PASP <35 mmHg, assessed by intraoperative TEE. Outcomes studied were poor coronary revascularization, postoperative arrhythmias, myocardial infarction, respiratory failure, intra-aortic balloon pump use, pacemaker dependence, significant inotrope use, prolonged intensive care unit stay, and the total length of stay in the hospital. Mortality analysis was not a part of this study since expected sample sizes were low. Results: Patients with PASP ≥35 mmHg had a higher risk of respiratory failure, increased inotrope use and prolonged hospital stay, although multivariate analysis failed to demonstrate an independent association of PASP with these outcomes. Diabetes mellitus (DM), peripheral vascular disease, low cardiac output and elevated mitral annular E/e' ratio were significantly associated with higher pulmonary arterial pressures. Multivariate analysis showed that PASP was independently associated with higher mitral annular E/e' ratio. Conclusions: Our study, therefore, suggests that higher PASP may predict higher left ventricular filling pressures, and although elevated PASP ≥35 mmHg may be associated with DM; peripheral vascular disease, lower intraoperative cardiac output, postoperative respiratory failure, higher inotrope use, and delayed hospital discharge, it is not an independent predictor of any of these variables.
topic cardiopulmonary bypass
coronary artery bypass graft
pulmonary
systolic pressure
transesophageal echocardiography
url http://www.annals.in/article.asp?issn=0971-9784;year=2020;volume=23;issue=4;spage=453;epage=459;aulast=Subramanian
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