Novel Genetic Markers for Early Detection of Elevated Breast Cancer Risk in Women
This study suggests that two newly discovered variants in the <i>MSH2</i> gene, which codes for a DNA mismatch repair (MMR) protein, can be associated with a high risk of breast cancer. While variants in the MSH2 gene are known to be linked with an elevated cancer risk, the MSH2 gene is...
Main Authors: | Bohua Wu, Yunhui Peng, Julia Eggert, Emil Alexov |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/19/4828 |
Similar Items
-
Evaluation of performance of leading algorithms for variant pathogenicity predictions and designing a combinatory predictor method: application to Rett syndrome variants
by: Satishkumar Ranganathan Ganakammal, et al.
Published: (2019-11-01) -
Structural Perspective on Revealing and Altering Molecular Functions of Genetic Variants Linked with Diseases
by: Yunhui Peng, et al.
Published: (2019-01-01) -
Some aspects of molecular diagnostics in Lynch syndrome
by: Kurzawski Grzegorz
Published: (2006-12-01) -
Lynch Syndrome Germline Mutations in Breast Cancer: Next Generation Sequencing Case-Control Study of 1,263 Participants
by: Aleksey G. Nikitin, et al.
Published: (2020-05-01) -
MSH2 Overexpression Due to an Unclassified Variant in 3′-Untranslated Region in a Patient with Colon Cancer
by: Raffaella Liccardo, et al.
Published: (2020-06-01)