Multiple cytokines are released when blood from patients with tuberculosis is stimulated with Mycobacterium tuberculosis antigens.
<h4>Background</h4>Mycobacterium tuberculosis (Mtb) infection may cause overt disease or remain latent. Interferon gamma release assays (IGRAs) detect Mtb infection, both latent infection and infection manifesting as overt disease, by measuring whole-blood interferon gamma (IFN-γ) respon...
Main Authors: | Kathryn L Kellar, Jennifer Gehrke, Stephen E Weis, Aida Mahmutovic-Mayhew, Blachy Davila, Margan J Zajdowicz, Robin Scarborough, Philip A LoBue, Alfred A Lardizabal, Charles L Daley, Randall R Reves, John Bernardo, Brandon H Campbell, William C Whitworth, Gerald H Mazurek |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22132075/pdf/?tool=EBI |
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