Kainic Acid and MPP+ Induce Upregulation of GLT-1 in Neuroblastoma and Glia Cells

Kainic Acid and MPP+ Induce Upregulation of GLT-1 in Neuroblastoma and Glia Cells

Objective:Glutamate is the major excitatory transmitter in the brain. The excessive glutamate will lead to excitotoxicity. Glutamate transporter-1 (GLT-1) is the major transporter that performs 95% of the glutamate clearance contributing to normal neuronal function and preventing excitotoxicity. In...

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Bibliographic Details
Main Authors:	Rabia UYARICI, Ceylan AK, Gizem DÖNMEZ YALÇIN
Format:	Article
Language:	English
Published:	Galenos Publishing House 2021-04-01
Series:	Bezmiâlem Science
Subjects:	excitotoxicity glt-1 glutamate mpp+ kainic acid mrna
Online Access:	http://bezmialemscience.org/archives/archive-detail/article-preview/kainic-acid-and-mpp-nduce-upregulation-of-glt-1-in/47248

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