Clinical Results of Hypomethylating Agents in AML Treatment

Clinical Results of Hypomethylating Agents in AML Treatment

Epigenetic changes play an important role in the development of acute myeloid leukemia (AML). Unlike gene mutations, epigenetic changes are potentially reversible, which makes them attractive for therapeutic intervention. Agents that affect epigenetics are the DNA methyltransferase inhibitors, azaci...

Full description

Bibliographic Details
Main Authors: Marjan Cruijsen, Michael Lübbert, Pierre Wijermans, Gerwin Huls
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Journal of Clinical Medicine
Subjects:
AML
azacitidine
decitabine
hypomethylating agents
elderly
epigenetics
Online Access:http://www.mdpi.com/2077-0383/4/1/1

Similar Items

Similar Items