Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease

Background: Myoclonus and encephalopathy are unusual in patients with Parkinson’s disease (PD). Case report: We describe the case of a 59-year-old male with PD who developed myoclonus and encephalopathy. Underlying hypothyroidism was revealed after admission and treated with levothyroxine. Myoclo...

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Main Authors: Gwanhee Ehm, Han-Joon Kim, Beomseok Jeon
Format: Article
Language:English
Published: Ubiquity Press 2017-10-01
Series:Tremor and Other Hyperkinetic Movements
Subjects:
PD
Online Access:https://tremorjournal.org/index.php/tremor/article/view/505
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spelling doaj-3bce764fe2ac4a52b90809ee50aa1b012021-04-02T16:53:31ZengUbiquity PressTremor and Other Hyperkinetic Movements2160-82882160-82882017-10-011210.7916/D8BP0F9F347Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s DiseaseGwanhee Ehm0Han-Joon Kim1Beomseok Jeon2National Medical Center, Seoul, KoreaSeoul National UniversitySeoul National UniversityBackground: Myoclonus and encephalopathy are unusual in patients with Parkinson’s disease (PD). Case report: We describe the case of a 59-year-old male with PD who developed myoclonus and encephalopathy. Underlying hypothyroidism was revealed after admission and treated with levothyroxine. Myoclonus and encephalopathy were completely resolved following thyroid hormone replacement. Discussion: Hypothyroidism can cause reversible myoclonus and encephalopathy along with unusual aggravation of parkinsonism symptoms in patients with PD.https://tremorjournal.org/index.php/tremor/article/view/505NeurologyHypothyroidismEncephalopathyParkinson's diseasePDMyoclonusHormone replacementCase study
collection DOAJ
language English
format Article
sources DOAJ
author Gwanhee Ehm
Han-Joon Kim
Beomseok Jeon
spellingShingle Gwanhee Ehm
Han-Joon Kim
Beomseok Jeon
Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease
Tremor and Other Hyperkinetic Movements
Neurology
Hypothyroidism
Encephalopathy
Parkinson's disease
PD
Myoclonus
Hormone replacement
Case study
author_facet Gwanhee Ehm
Han-Joon Kim
Beomseok Jeon
author_sort Gwanhee Ehm
title Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease
title_short Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease
title_full Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease
title_fullStr Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease
title_full_unstemmed Hypothyroidism-induced Reversible Encephalopathy as a Cause of Aggravation of Parkinsonism and Myoclonus in Parkinson’s Disease
title_sort hypothyroidism-induced reversible encephalopathy as a cause of aggravation of parkinsonism and myoclonus in parkinson’s disease
publisher Ubiquity Press
series Tremor and Other Hyperkinetic Movements
issn 2160-8288
2160-8288
publishDate 2017-10-01
description Background: Myoclonus and encephalopathy are unusual in patients with Parkinson’s disease (PD). Case report: We describe the case of a 59-year-old male with PD who developed myoclonus and encephalopathy. Underlying hypothyroidism was revealed after admission and treated with levothyroxine. Myoclonus and encephalopathy were completely resolved following thyroid hormone replacement. Discussion: Hypothyroidism can cause reversible myoclonus and encephalopathy along with unusual aggravation of parkinsonism symptoms in patients with PD.
topic Neurology
Hypothyroidism
Encephalopathy
Parkinson's disease
PD
Myoclonus
Hormone replacement
Case study
url https://tremorjournal.org/index.php/tremor/article/view/505
work_keys_str_mv AT gwanheeehm hypothyroidisminducedreversibleencephalopathyasacauseofaggravationofparkinsonismandmyoclonusinparkinsonsdisease
AT hanjoonkim hypothyroidisminducedreversibleencephalopathyasacauseofaggravationofparkinsonismandmyoclonusinparkinsonsdisease
AT beomseokjeon hypothyroidisminducedreversibleencephalopathyasacauseofaggravationofparkinsonismandmyoclonusinparkinsonsdisease
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